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Advanced filters: Author: Frederik Van Leemputte Clear advanced filters

  • Yeast and cancer cells both favor sugar fermentation in aerobic conditions. Here the authors describe a conserved mechanism from yeast to mammals where the glycolysis intermediate fructose-1,6-bisphosphate binds Cdc25/Sos1 and couples increased glycolytic flux to increased Ras proto-oncoprotein activity.

    • Ken Peeters
    • Frederik Van Leemputte
    • Johan M. Thevelein
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-15