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Effectiveness of ChAdOx1-S COVID-19 booster vaccination against the Omicron and Delta variants in England

Vaccine effectiveness of a ChAdOx1-S booster was estimated in a test-negative case-control study in England. Protection was found to be moderate against mild disease but remained high and comparable to that of an mRNA booster against hospitalisation with Omicron.

Freja Cordelia Møller Kirsebom
Nick Andrews
Jamie Lopez Bernal
ResearchOpen Access12 Dec 2022
Nature Communications

Volume: 13, P: 1-9
Effectiveness of COVID-19 vaccines against Omicron and Delta hospitalisation, a test negative case-control study

SARS-CoV-2 variants of concern have been associated with reduced vaccine effectiveness, even after a booster dose. In this study, authors aim to estimate vaccine effectiveness against hospitalisation with the Omicron and Delta variants, using different definitions of hospitalisation in secondary care data.

Julia Stowe
Nick Andrews
Jamie Lopez Bernal
ResearchOpen Access30 Sept 2022
Nature Communications

Volume: 13, P: 1-8
Effectiveness of COVID-19 booster vaccines against COVID-19-related symptoms, hospitalization and death in England

A test-negative case–control analysis of data from the National Immunisation Management System in England demonstrates significant levels of increased protection against hospitalization or death from COVID with mRNA booster vaccines following a primary two-dose course of either ChAdOx1-S or BNT162b2 vaccines.

Nick Andrews
Julia Stowe
Jamie Lopez Bernal
ResearchOpen Access14 Jan 2022
Nature Medicine

Volume: 28, P: 831-837
Lentiviral and AAV-mediated expression of palivizumab offer protection against Respiratory Syncytial Virus infection

Agata Antepowicz
Omar Habib
Stephen C. Hyde
ResearchOpen Access03 Aug 2021
Scientific Reports

Volume: 11, P: 1-12
Neutrophils do not impact viral load or the peak of disease severity during RSV infection

Freja Kirsebom
Christina Michalaki
Cecilia Johansson
ResearchOpen Access24 Jan 2020
Scientific Reports

Volume: 10, P: 1-12
Neutrophil recruitment and activation are differentially dependent on MyD88/TRIF and MAVS signaling during RSV infection

Freja C. M. Kirsebom
Fahima Kausar
Cecilia Johansson
ResearchOpen Access29 Jul 2019
Mucosal Immunology

Volume: 12, P: 1244-1255
Neutrophils in respiratory viral infections

Cecilia Johansson
Freja C. M. Kirsebom
ReviewsOpen Access23 Mar 2021
Mucosal Immunology

Volume: 14, P: 815-827

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Effectiveness of ChAdOx1-S COVID-19 booster vaccination against the Omicron and Delta variants in England

Effectiveness of COVID-19 vaccines against Omicron and Delta hospitalisation, a test negative case-control study

Effectiveness of COVID-19 booster vaccines against COVID-19-related symptoms, hospitalization and death in England

Lentiviral and AAV-mediated expression of palivizumab offer protection against Respiratory Syncytial Virus infection

Neutrophils do not impact viral load or the peak of disease severity during RSV infection

Neutrophil recruitment and activation are differentially dependent on MyD88/TRIF and MAVS signaling during RSV infection

Neutrophils in respiratory viral infections

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