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Showing 1–2 of 2 results
Advanced filters: Author: G. Babnigg Clear advanced filters

  • The development of direct-acting antivirals to combat COVID-19 remains an important goal. Here the authors design covalent inhibitors that target the papain-like protease from SARS-CoV-2. The most promising inhibitor blocks viral replication in mammalian cells.

    • Brian C. Sanders
    • Suman Pokhrel
    • Jerry M. Parks
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • Metallo-β-lactamases cleave β-lactam moiety of many broadly used antibiotics. Here the authors captured mechanistic details of the enzyme catalyzed reaction using time-resolved xray synchrotron serial crystallography.

    • M. Wilamowski
    • D. A. Sherrell
    • A. Joachimiak
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-12