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Showing 1–10 of 10 results
Advanced filters: Author: G. Eric Bastien Clear advanced filters

  • The identification of T cell epitopes is a critical step in understanding the immune response to infection and in designing vaccine based approaches. Here the authors introduce a frame work of antigen discovery called MHCvalidator and Epitrack to identify new antigenic features for T-cell COVID-19 vaccines and characterise a novel non-canonical epitope from a truncated Spike variant and mutation of an immunodominant epitope in the BNT162b4 vaccine.

    • Kevin A. Kovalchik
    • David J. Hamelin
    • Etienne Caron
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-22

  • How biodiversity is linked to multiple ecosystem functions is not fully understood. Here, the authors show that a new mechanism, which they term the 'jack-of-all-trades' effect, best explains patterns of tree diversity and ecosystem multifunctionality in European forests.

    • Fons van der Plas
    • Peter Manning
    • Markus Fischer
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-11

  • Electric fields typically break symmetry when applied as a stimulus to materials. Here, by forming a superlattice of BiFeO3 and TbScO3, it is shown that an electric field can repeatedly stabilize mixed-phase polar and antipolar BiFeO3.

    • Lucas Caretta
    • Yu-Tsun Shao
    • Ramamoorthy Ramesh
    Research
    Nature Materials
    Volume: 22, P: 207-215

  • Despite observations from a hot-water-drilled access hole showing warm ocean waters beneath Thwaites Glacier Eastern Ice Shelf, the basal melt rate is strongly suppressed due to the low current speeds and strong density stratification.

    • Peter E. D. Davis
    • Keith W. Nicholls
    • Keith Makinson
    ResearchOpen Access
    Nature
    Volume: 614, P: 479-485

  • Phytoplankton and plant plastids have distinct evolutionary origins and membrane organization. Here Floriet al. show that diatom photosynthetic complexes spatially segregate into interconnected subdomains within loose thylakoid stacks enabling fast diffusion of electron carriers and efficient photosynthesis

    • Serena Flori
    • Pierre-Henri Jouneau
    • Giovanni Finazzi
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-9

  • The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.

    • Gary A Churchill
    • David C Airey
    • Fei Zou
    Comments & Opinion
    Nature Genetics
    Volume: 36, P: 1133-1137