Moral-Sanz, Fernández-Carrasco and colleagues identify senolytic properties of sea anemone-derived pore-forming toxins, with selectivity mediated by senescence-associated lipid profiles. An optimized senotoxin improves the efficacy of chemotherapy in mouse models.
- Javier Moral-Sanz
- Isabel Fernández-Carrasco
- Maria P. Ikonomopoulou