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The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila

Dicer proteins direct RNA-interference activities. Imler and colleagues show that Dicer-2 induces Vago-dependent antiviral response in flies and that Dicer proteins are related to RIG-I viral sensors.

Safia Deddouche
Nicolas Matt
Jean-Luc Imler
Research26 Oct 2008
Nature Immunology

Volume: 9, P: 1425-1432
In situ structures of the portal-neck-tail complex of bacteriophage T4 inform a viral genome positioning mechanism

Icosahedral viruses package their genomes into a proteinaceous capsid to near crystalline density. Here, the authors report cryo-EM-based insights into the post-packaging genome positioning, virion assembly and maturation mechanisms in the tailed bacteriophage T4.

Andrei Fokine
Jingen Zhu
Venigalla B. Rao
ResearchOpen Access20 Feb 2026
Nature Communications

Volume: 17, P: 1-15
Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti

Aedes aegypti can act as a vector for viral pathogens but the mechanism of viral resistance and evolving host-pathogen tolerance are poorly understood. Here the authors structurally characterise a duplicated pair of interacting Toll immunoreceptors and the cytokine ligand Spaetzle1C and show their dose-dependent function and mechanism of activation.

Yoann Saucereau
Thomas H. Wilson
Monique Gangloff
ResearchOpen Access30 Aug 2022
Nature Communications

Volume: 13, P: 1-14
Reactions of Cytochrome-c with Methyl Linoleate Hydroperoxide

A. BANKS
E. EDDIE
J. G. M. SMITH
Research03 Jun 1961
Nature

Volume: 190, P: 908-909
'Stimulation Crystals' and Twin-formation in Recrystallized Aluminium

W. G. BURGERS
Research19 Jan 1946
Nature

Volume: 157, P: 76-77
Polyphase Folding in the Caledonides South of the Scottish Highlands

D. G. HELM
B. ROBERTS
A. SIMPSON
Research14 Dec 1963
Nature

Volume: 200, P: 1060-1062
Effect of Anti-histamine Substances on Cold Vasodilatation in the Finger

G. C. WHITTOW
Research10 Sept 1955
Nature

Volume: 176, P: 511-512
‘Heterochromatin’

JOHN R. BAKER
H. G. CALLAN
Research05 Aug 1950
Nature

Volume: 166, P: 227-228
Differentiation of Receptor Systems activated by Sympathomimetic Amines

A. M. LANDS
A. ARNOLD
T. G. BROWN JUN.
Research06 May 1967
Nature

Volume: 214, P: 597-598
The Isomeric Trithioaldehydes

G. M. BENNETT
Research11 Oct 1947
Nature

Volume: 160, P: 502
A New Reaction of Ethylenic Double Bonds

A. QUILICO
G. STAGNO D'ALCONTRES
P. GRÜNANGER
Research05 Aug 1950
Nature

Volume: 166, P: 226-227
Infra-Red Spectrum of C_nD_{2n + 2} and the 'Long-Chain Frequency' in Paraffins

N. SHEPPARD
G. B. B. M. SUTHERLAND
Research31 May 1947
Nature

Volume: 159, P: 739-740
Loss of NUMB drives aggressive bladder cancer via a RHOA/ROCK/YAP signaling axis

The transition from non-muscle-invasive bladder cancer (NMIBC) to muscle-invasive bladder cancer (MIBC) is associated with poorer patient prognosis. Here, the authors investigate NUMB loss as a driver of the NMIBC-to-MIBC transition and identify a RHOA/ROCK/YAP signaling pathway as a therapeutic vulnerability.

F. A. Tucci
R. Pennisi
S. Pece
ResearchOpen Access03 Dec 2024
Nature Communications

Volume: 15, P: 1-24
Pten deletion in RIP-Cre neurons protects against type 2 diabetes by activating the anti-inflammatory reflex

A new study by Minna Woo and colleagues shows that a neuronal relay from the brain to the adipose tissue regulates whole-body insulin sensitivity by affecting macrophage function, and thus inflammation, in the periphery. These results suggest that a centrally mediated anti-inflammatory reflex exists to regulate metabolic health.

Linyuan Wang
Darren Opland
Minna Woo
Research20 Apr 2014
Nature Medicine

Volume: 20, P: 484-492
Biological magnetic resonance imaging using laser-polarized ¹²⁹Xe

M. S. Albert
G. D. Cates
A. Wishnia
Research21 Jul 1994
Nature

Volume: 370, P: 199-201
Interaction of Defect and Domain Structures of Triglycine Sulphate Crystals in Ferroelectric and Paraelectric States

G. I. DISTLER
V. P. KONSTANTINOVA
G. A. TOLMACHEVA
Research25 May 1968
Nature

Volume: 218, P: 762-765
Characterisation of Aleutian disease antigens

G. W. NOTANI
E. C. HAHN
A. J. KENYON
Research06 May 1976
Nature

Volume: 261, P: 56-58
Revealing Real-Time Emotional Responses: a Personalized Assessment based on Heartbeat Dynamics

Gaetano Valenza
Luca Citi
Riccardo Barbieri
ResearchOpen Access21 May 2014
Scientific Reports

Volume: 4, P: 1-13
Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor

Different phosphorylation patterns created by GRK2 and GRK5 on the C-terminal tail of ACKR3 lead to distinct structural arrangements and dynamics of G-protein-coupled receptor–arrestin complexes, potentially explaining diverse cellular outcomes.

Qiuyan Chen
Christopher T. Schafer
John J. G. Tesmer
Research21 May 2025
Nature

Volume: 643, P: 280-287
CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer

Finding biomarkers for targeted therapy is a promising approach to treat cancer. Here, the authors show that in breast cancer preclinical models and patients, CDK12 promotes tumourigenesis but induces selective vulnerability to therapies that target folate one-carbon metabolism.

M. G. Filippone
D. Gaglio
S. Pece
ResearchOpen Access12 May 2022
Nature Communications

Volume: 13, P: 1-19
Gastric dysmotility in Parkinson's disease is not caused by alterations of the gastric pacemaker cells

Konstantin G. Heimrich
Veit Y. P. Jacob
Tino Prell
ResearchOpen Access26 Jul 2019
npj Parkinson's Disease

Volume: 5, P: 1-6
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation

Post-transplantation relapse in acute myeloid leukemia patients without genomic loss of HLA is driven by transcriptional alterations in antigen presentation and T cell costimulation genes.

Cristina Toffalori
Laura Zito
Luca Vago
Research25 Mar 2019
Nature Medicine

Volume: 25, P: 603-611
Leçons sur les Séries Divergentes

G. B. M.
Books & Arts07 Nov 1901
Nature

Volume: 65, P: 2-3
The Action of the Nerves of the Batrachian Heart in Relation to Temperature and Endocardiac Pressure

G. N. STEWART
News09 Apr 1891
Nature

Volume: 43, P: 548
Contribution à l'étude de la structure moléculaire

E. F. G. HERINGTON
Books & Arts14 May 1949
Nature

Volume: 163, P: 746
Adjuvant role of SeptiFast to improve the diagnosis of sepsis in a large cohort of hematological patients

Raffaella Greco
Maria Chiara Barbanti
Fabio Ciceri
Research12 Jan 2018
Bone Marrow Transplantation

Volume: 53, P: 410-416
Effect of remote ischemic conditioning on the immune-inflammatory profile in patients with traumatic hemorrhagic shock in a randomized controlled trial

C. H. Leung
S. B. Rizoli
O. D. Rotstein
ResearchOpen Access29 Apr 2023
Scientific Reports

Volume: 13, P: 1-14
Haploidentical HSCT: a 15-year experience at San Raffaele

C Bonini
J Peccatori
F Ciceri
Research03 Jun 2015
Bone Marrow Transplantation

Volume: 50, P: S67-S71
Precision-based exercise as a new therapeutic option for children and adolescents with haematological malignancies

Francesca Lanfranconi
W. Zardo
A. Balduzzi
ResearchOpen Access30 Jul 2020
Scientific Reports

Volume: 10, P: 1-13
Shared acquired genomic changes in zebrafish and human T-ALL

L A Rudner
K H Brown
J K Frazer
Research09 May 2011
Oncogene

Volume: 30, P: 4289-4296
Chimerism analysis for clinicians: a review of the literature and worldwide practices

Amanda G. Blouin
Medhat Askar
Reviews26 Jan 2022
Bone Marrow Transplantation

Volume: 57, P: 347-359
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation

L Crucitti
R Crocchiolo
L Vago
Research05 Nov 2014
Leukemia

Volume: 29, P: 1143-1152
The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy

S Michiorri
V Gelmetti
G Casari
Research08 Jan 2010
Cell Death & Differentiation

Volume: 17, P: 962-974
Induction of eosinophil apoptosis by hydrogen peroxide promotes the resolution of allergic inflammation

A C Reis
A L Alessandri
V Pinho
ResearchOpen Access12 Feb 2015
Cell Death & Disease

Volume: 6, P: e1632
Setting the conditions for efficient, robust and reproducible generation of functionally active neurons from adult subventricular zone-derived neural stem cells

D Goffredo
L Conti
E Cattaneo
Research12 Sept 2008
Cell Death & Differentiation

Volume: 15, P: 1847-1856
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors

J Peccatori
A Forcina
F Ciceri
Research04 Jun 2014
Leukemia

Volume: 29, P: 396-405
Longitudinal qPCR monitoring of nucleophosmin 1 mutations after allogeneic hematopoietic stem cell transplantation to predict AML relapse

E Xue
C Tresoldi
L Vago
Correspondence07 Dec 2015
Bone Marrow Transplantation

Volume: 51, P: 466-469
Low MCL-1 mRNA expression correlates with prolonged survival in B-cell chronic lymphocytic leukemia

L Véronèse
O Tournilhac
A Tchirkov
Correspondence29 Nov 2007
Leukemia

Volume: 22, P: 1291-1293

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