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Regulatory (pan-)genome of an obligate intracellular pathogen in the PVC superphylum

Marie de Barsy
Antonio Frandi
Patrick H Viollier
ResearchOpen Access08 Mar 2016
The ISME Journal

Volume: 10, P: 2129-2144
Human Smc5/6 recognises transcription-generated positive DNA supercoils

The study reveals a novel relationship between the human Smc5/6 complex and DNA topology during transcription and emphasizes the importance of DNA topology sensing in the defense against extrachromosomal genetic threats.

Aurélie Diman
Gaël Panis
Michel Strubin
ResearchOpen Access06 Sept 2024
Nature Communications

Volume: 15, P: 1-17
Uncovering enzymatic tools promoting lignocellulose breakdown in the anaerobic bacterium Ruminiclostridium cellulolyticum

Ruminiclostridium cellulolyticum’s lignocellulose anaerobic degradation involves two cellulosomal SGNH hydrolases targeting plant cell wall esterified hydroxycinnamic acids, a new function promoting the polysaccharides access via lignin unzipping.

Nicolas Vita
Marion Holmière
Henri-Pierre Fierobe
ResearchOpen Access04 Dec 2025
Communications Biology

Volume: 9, P: 1-16

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