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Showing 1–3 of 3 results
Advanced filters: Author: Gabriel Aughey Clear advanced filters

  • Conventional methods cannot reveal transient transcription factors (TFs) and targets interactions. Here, Alvarez et al. capture both stable and transient TF-target interactions by time-series ChIP-seq and/or DamID-seq in a cell-based TF perturbation system and show NLP7 as a master TF to initiate a rapid nitrogen-response cascade.

    • José M. Alvarez
    • Anna-Lena Schinke
    • Gloria M. Coruzzi
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13

  • A chromatin accessibility atlas of 240,919 cells in the adult and developing Drosophila brain reveals 95,000 enhancers, which are integrated in cell-type specific enhancer gene regulatory networks and decoded into combinations of functional transcription factor binding sites using deep learning.

    • Jasper Janssens
    • Sara Aibar
    • Stein Aerts
    Research
    Nature
    Volume: 601, P: 630-636