Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–6 of 6 results
Advanced filters: Author: Gabriel Lepousez Clear advanced filters

  • Classically, corticofugal feedback projections that adjust sensory processing are excitatory. Here, the authors uncover the presence of top-down inhibitory projections from cortical GABAergic neurons in the olfactory system, which directly inhibit olfactory bulb circuits.

    • Camille Mazo
    • Antoine Nissant
    • Gabriel Lepousez
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-20

  • Whether and how cannabinoid type-1 receptors impact sensory functions in vivo is largely unknown. Here, authors show that their endogenous activity controls network dynamics in the olfactory piriform cortex and the ability of mice to detect odorants.

    • Geoffrey Terral
    • Evan Harrell
    • Lisa Roux
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • The gut microbiota may contribute to depression, but the underlying mechanism is not well understood. Here the authors use a mouse model of stress induced depression to demonstrate that behavioural changes conferred by fecal transplant from stressed to naïve mice require the endocannabinoid system.

    • Grégoire Chevalier
    • Eleni Siopi
    • Pierre-Marie Lledo
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15

  • This study shows that activation of cannabinoid type-1 (CB1) receptors in the olfactory bulb increases odor detection and food intake in hungry mice. The authors show that this function is mediated by CB1-dependent attenuation of excitatory corticofugal synaptic transmission onto inhibitory granule cells and disinhibition of mitral cells in the main olfactory bulb.

    • Edgar Soria-Gómez
    • Luigi Bellocchio
    • Giovanni Marsicano
    Research
    Nature Neuroscience
    Volume: 17, P: 407-415

  • Using optogenetic activation of adult-born neurons in the mouse olfactory bulb, the authors find that selective stimulation of new interneurons generated during adulthood, but not earlier, accelerates learning in a two-odor discrimination task and improves olfactory memory.

    • Mariana Alonso
    • Gabriel Lepousez
    • Pierre-Marie Lledo
    Research
    Nature Neuroscience
    Volume: 15, P: 897-904