GIRK channels are activated by Gβγ; quantitative aspects are debatable. Here, the authors measure interaction affinities in living cell membranes and uncover roles of Gγ prenylation and a Gβγ docking site in GIRK1 in efficient channel activation.
- Reem Handklo-Jamal
- Tal Keren Raifman
- Nathan Dascal
