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Showing 1–20 of 20 results

Advanced filters: Author: Gangqing Hu Clear advanced filters

Mapping histone modifications in low cell number and single cells using antibody-guided chromatin tagmentation (ACT-seq)

The authors introduce ACT-seq: a Tn5-based method for rapidly profiling epigenetic marks in bulk-cell and single-cell samples. ACT-seq avoids many laborious or time-consuming steps required for similar techniques including chromatin fragmentation and end repair.

Benjamin Carter
Wai Lim Ku
Keji Zhao
ResearchOpen Access20 Aug 2019
Nature Communications

Volume: 10, P: 1-5
Erratum: Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment

Chao Zhong
Kairong Cui
Jinfang Zhu
Amendments and Corrections22 Mar 2016
Nature Immunology

Volume: 17, P: 469
Erratum: Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment

Chao Zhong
Kairong Cui
Jinfang Zhu
Amendments and Corrections19 Jan 2016
Nature Immunology

Volume: 17, P: 214
Publisher Correction: Principles of nucleosome organization revealed by single-cell micrococcal nuclease sequencing

Binbin Lai
Weiwu Gao
Keji Zhao
Amendments and Corrections06 Nov 2018
Nature

Volume: 564, P: E17
Preliminary evaluation of ChatGPT model iterations in emergency department diagnostics

Jinge Wang
Kenneth Shue
Gangqing Hu
ResearchOpen Access26 Mar 2025
Scientific Reports

Volume: 15, P: 1-9
Author Correction: Mapping histone modifications in low cell number and single cells using antibody-guided chromatin tagmentation (ACT-seq)

Benjamin Carter
Wai Lim Ku
Keji Zhao
Amendments and CorrectionsOpen Access01 Sept 2020
Nature Communications

Volume: 11, P: 1
Trac-looping measures genome structure and chromatin accessibility

Insertion of a bivalent linker between two regions of interest allows chromatin contacts to be probed without proximity ligation.

Binbin Lai
Qingsong Tang
Keji Zhao
Research27 Aug 2018
Nature Methods

Volume: 15, P: 741-747
Molecular mechanisms limiting the AAV gene therapy treatment window in mouse models of blue cone monochromacy

AAV gene therapy treatment of the two most common blue cone monochromacy (BCM) mutations reveals similar limited therapeutic windows, which may be improved by the utilization of newly identified upregulated cone specific promoters in aged BCM cones.

Brooke A. Brothers
Emily R. Sechrest
Wen-Tao Deng
ResearchOpen Access24 Nov 2025
Communications Biology

Volume: 8, P: 1-11
MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping

Zhao and colleagues show that the histone lysine methyltransferase MLL4 primes the Foxp3 locus for transcriptional activation in thymus-derived and inducible regulatory T cells.

Katarzyna Placek
Gangqing Hu
Keji Zhao
Research31 Jul 2017
Nature Immunology

Volume: 18, P: 1035-1045
Co-culture model of B-cell acute lymphoblastic leukemia recapitulates a transcription signature of chemotherapy-refractory minimal residual disease

Stephanie L. Rellick
Gangqing Hu
Laura F. Gibson
ResearchOpen Access04 Aug 2021
Scientific Reports

Volume: 11, P: 1-10
Expression and regulation of intergenic long noncoding RNAs during T cell development and differentiation

Intergenic long noncoding RNAs (lincRNAs) regulate gene expression in various tissues. Zhao and colleagues identify 1,524 lincRNA clusters in thymocytes and mature T cell subsets and reveal dynamic and cell-specific patterns of lincRNA expression during T cell differentiation.

Gangqing Hu
Qingsong Tang
Keji Zhao
Research22 Sept 2013
Nature Immunology

Volume: 14, P: 1190-1198
Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment

Group 3 innate lymphoid cells have low expression of the transcription factor GATA-3. Zhu and colleagues show that despite its low expression, GATA-3 is essential for the homeostasis, further maturation and effector function of lineage-committed group 3 innate lymphoid cells.

Chao Zhong
Kairong Cui
Jinfang Zhu
Research23 Nov 2015
Nature Immunology

Volume: 17, P: 169-178
ChIP-Seq: technical considerations for obtaining high-quality data

Benjamin L Kidder
Gangqing Hu
Keji Zhao
Comments & Opinion20 Sept 2011
Nature Immunology

Volume: 12, P: 918-922
Single-cell chromatin immunocleavage sequencing (scChIC-seq) to profile histone modification

Covalent linking of a histone-modification-specific antibody to MNase allows for the isolation of fragments with the desired histone mark, which can be amplified and sequenced. This approach is sensitive enough to profile histone modifications in single cells.

Wai Lim Ku
Kosuke Nakamura
Keji Zhao
Research28 Mar 2019
Nature Methods

Volume: 16, P: 323-325
Principles of nucleosome organization revealed by single-cell micrococcal nuclease sequencing

Single-cell micrococcal nuclease sequencing simultaneously measures chromatin accessibility and genome-wide nucleosome positioning in single cells to reveal principles of nucleosome organization.

Binbin Lai
Weiwu Gao
Keji Zhao
Research26 Sept 2018
Nature

Volume: 562, P: 281-285
Correction: Corrigendum: The conservation and signatures of lincRNAs in Marek’s disease of chicken

Yanghua He
Yi Ding
Jiuzhou Song
Amendments and CorrectionsOpen Access27 Jan 2016
Scientific Reports

Volume: 6, P: 1
Scientific figures interpreted by ChatGPT: strengths in plot recognition and limits in color perception

Jinge Wang
Qing Ye
Gangqing Hu
ResearchOpen Access05 Apr 2024
npj Precision Oncology

Volume: 8, P: 1-8
Nuclear Aurora-A kinase-induced hypoxia signaling drives early dissemination and metastasis in breast cancer: implications for detection of metastatic tumors

Kristina M. Whately
Maria A. Voronkova
Elena N. Pugacheva
Research29 Jul 2021
Oncogene

Volume: 40, P: 5651-5664
Negative reciprocal regulation between Sirt1 and Per2 modulates the circadian clock and aging

Rui-Hong Wang
Tingrui Zhao
Chu-Xia Deng
ResearchOpen Access27 Jun 2016
Scientific Reports

Volume: 6, P: 1-15
The conservation and signatures of lincRNAs in Marek’s disease of chicken

Yanghua He
Yi Ding
Jiuzhou Song
ResearchOpen Access16 Oct 2015
Scientific Reports

Volume: 5, P: 1-17