In complex reaction systems featuring intricate product and pathway possibilities, achieving simultaneous control over multiple selectivities remains highly challenging. Now it has been demonstrated that biomimetic peptide–phosphonium salts can concurrently impart stepwise and stereochemical control in the asymmetric Atherton–Todd reaction, which enables efficient access to diverse P-stereogenic platform molecules.
- Fan Wang
- Jian-Ping Tan
- Tianli Wang
