Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–5 of 5 results
Advanced filters: Author: Ganna Panasyuk Clear advanced filters

  • Molecular factors, regulating the expression of specific glycolytic enzymes that favour biosynthetic processes, have remained unknown. Panasyuket al. identify PPARγ as a novel transcription factor turning on pyruvate kinase M2 and hexokinase 2, which are frequently upregulated in pathophysiological growth.

    • Ganna Panasyuk
    • Catherine Espeillac
    • Mario Pende
    ResearchOpen Access
    Nature Communications
    Volume: 3, P: 1-9

  • Peroxisome Proliferator Activated Receptor alpha (PPARα) drives fatty acid catabolism. Here, the authors show that in liver of autophagy deficient class 3 phosphoinositide 3-kinase mutant mice PPARα transcriptional repressors fail to degrade in lysosomes and accumulate leading to PPARα inhibition and blunted transcriptional responses during fasting.

    • Anton Iershov
    • Ivan Nemazanyy
    • Ganna Panasyuk
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-18

  • Alkhoury et al. show that the class 3 phosphatidylinositol-3-kinase Vps15 subunit coactivates the circadian clock transcription factor Bmal1–Clock for metabolic rhythmicity in the liver and promotes pro-anabolic de novo purine synthesis.

    • Chantal Alkhoury
    • Nathaniel F. Henneman
    • Ganna Panasyuk
    ResearchOpen Access
    Nature Cell Biology
    Volume: 25, P: 975-988

  • PI3K is activated as a result of insulin receptor (IR) signalling. Here the authors show that activation of specific class III PI3Ks in response to insulin promotes IR endocytosis and lysosomal degradation, providing negative feedback on IR signalling by reducing the time IR is activated.

    • Ivan Nemazanyy
    • Guillaume Montagnac
    • Ganna Panasyuk
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-16