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Advanced filters: Author: Gavin Fredrickson Clear advanced filters

  • Patterson, Firulyova, et al. report that TREM2 is a key regulator of foamy macrophage differentiation. Myeloid-specific deletion of Trem2 caused increased macrophage susceptibility to cholesterol-mediated toxicity and cell death and significantly attenuated atherosclerotic plaque progression in mice.

    • Michael T. Patterson
    • Maria M. Firulyova
    • Jesse W. Williams
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 2, P: 1015-1031