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Showing 1–4 of 4 results

Advanced filters: Author: Gavin G. Rutledge Clear advanced filters

Finding the needle in the haystack

This month's Genome Watch discusses the potential of selective whole-genome amplification for overcoming the challenges of whole-genome sequencing of malaria parasites in clinical samples in which they are low in abundance.

Gavin G. Rutledge
Cristina V. Ariani
News13 Feb 2017
Nature Reviews Microbiology

Volume: 15, P: 136
Juggling resistance mutations

This month’s Genome Watch discusses how a better understanding of the genetic mechanisms of antimalarial drug resistance can maximize the utility of genomic surveillance programs in informing the most effective drug policy.

Gavin G. Rutledge
Roberto Amato
News27 Apr 2018
Nature Reviews Microbiology

Volume: 16, P: 332
Last parasite standing

This month's Genome Watch describes how whole-genome sequencing used for surveillance purposes has enabled the identification of new drug resistance markers in the malaria parasite.

Gavin G. Rutledge
Thomas D. Otto
News09 Dec 2016
Nature Reviews Microbiology

Volume: 15, P: 4
Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution

The genome sequences of the neglected human-infective malaria species Plasmodium malariae and P. ovale provide new insights into their biology that are pertinent to understanding their epidemiology and to the broader agenda of malaria elimination.

Gavin G. Rutledge
Ulrike Böhme
Thomas D. Otto
ResearchOpen Access25 Jan 2017
Nature

Volume: 542, P: 101-104