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Advanced filters: Author: Gayathri Soundarajan Clear advanced filters

  • How Japanese encephalitis virus (JEV) penetrates the blood-brain barrier (BBB) remains unclear. Here, using a genetic mouse model and a virulent JEV strain, the authors show that perivascular mast cells (MC) mediate JEV neuroinvasion and identify the MC-protease chymase as a potential therapeutic target.

    • Justin T. Hsieh
    • Abhay P. S. Rathore
    • Ashley L. St. John
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14