Synaptic plasticity at the cerebellar parallel fiber–Purkinje cell is mediated by calcium/calmodulin kinase II. In a knockout mouse line lacking the beta subunit of CaMKII, the authors show a bidirectional inversion of synaptic plasticity accompanying movement disorders and impaired motor learning.
- Geeske M van Woerden
- Freek E Hoebeek
- Ype Elgersma
