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A randomized controlled trial evaluating the selection of a single blastocyst for transfer by deep learning did not demonstrate noninferiority in clinical pregnancy rates when compared to trained embryologists using standard morphology criteria.

Hybrid superconductor-semiconductor devices offer a promising platform for topological superconductivity. Here, Ke and Moehle et al. create ballistic Josephson junctions in InSb quantum wells and use magnetic and electric fields to control their free energy landscape.

The behaviour of a superconductor can be altered by changing its symmetry properties. Coherently coupling two Josephson junctions breaks time-reversal and inversion symmetries, giving rise to a device with a controllable superconducting diode effect.

Controllable two-qubit interactions are necessary to build a functional quantum computer. Here the authors demonstrate fast, coherent swapping of two spin states mediated by a long, multi-electron quantum dot that could act as a tunable coupler mediating interactions between multiple qubits.

Measurements of anyons moving through a quantum point contact allow the extraction of their tunnelling exponent. This fully characterizes their topological order and confirms that they are well described by the Luttinger liquid theory.

Experimental observation of flux periodicity ϕ₀/2 for interference of the outermost edge mode of Fabry-Perot interferometers has been attributed to exotic electron pairing mechanisms. Here, the authors demonstrate that the interfering charges of a Fabry-Perot interferometer are single electrons

Inactivation of the ventral subiculum does not change existing schema cells in the orbitofrontal cortex (OFC) but aids their formation during new learning. This challenges the idea that the OFC relies on the hippocampus and suggests that these regions work in parallel to process different aspects of cognitive maps.

Rats learning to solve a succession of odour-sequence problems developed an orbitofrontal cortical representation that reflected the structure—or schema—common across problems.

Animals form cognitive maps of the world to guide behavior. This study shows that the lateral orbitofrontal cortex is essential for creating precise, outcome-specific cognitive maps during initial learning, but not for general map creation in itself.

Red cells infected with malaria express highly variable surface proteins that mediate cytoadherence, induce pathogenic effects and determine variant-specific immune responses (pages 358–360).

Sharpe et al. find that prior reward-learning experience can prime reward circuits to encode fear memories. This suggests prior experience can shape the way we learn, opening the neural boundaries for learning about particular types of information.

The entropy of a few-electron quantum system is measured for the first time by tracking the movement of charge in and out of the system. This could allow the unambiguous detection of Majorana fermions in solid state devices.

Scalable gate tunable superconducting qubits can be realized using a proximitized InAs two-dimensional electron gas.

Real-time adaptive control of a qubit has been demonstrated but limited to single-axis Hamiltonian estimation. Here the authors implement two-axis control of a singlet-triplet spin qubit with two fluctuating Hamiltonian parameters, resulting in improved quality of coherent oscillations.

Diodes exhibit non-reciprocal current–voltage relations, that is, the resistivity depends on the direction of the current flow. Now an array of Josephson junctions with large spin–orbit interaction acts as the superconducting version of a diode, where dissipation-free supercurrent flows in one direction, but not the other.

Topological kink modes are peculiar edge excitations that take place at domain boundaries of magnetic fields inside homogeneous materials. Here, the authors experimentally observe kink magnetoplasmons in a 2D electron gas using custom-shaped strong permanent magnets on top of a GaAs/AlGaAs heterojunction.

S. Matsuo et al. report tunneling spectroscopy measurements on a device consisting of two Josephson junctions (JJ) sharing a single superconducting electrode. In isolation, each JJ would host an Andreev bound state (ABS). In their coherently-coupled JJs, the authors report the formation of an Andreev molecule due to hybridization of the two ABSs.

Nuclear spins in gallium arsenide produce noise at discrete frequencies, which can be notch-filtered efficiently to extend coherence times of electron spin qubits to nearly 1 ms.

Despite recent demonstrations of coherent spin-state transfer in arrays of spin qubits via exchange interaction, all-matter spin-state teleportation is still out of reach. Here the authors provide evidence for conditional teleportation of quantum-dot spin states, entanglement swapping, and gate teleportation.

Information transfer between distant qubits suffers from spurious interactions and disorder. Here, the authors report up to an order of magnitude enhancement in the quality factor of a swap operation of eigenstates in a quantum dot chain, by using a periodic driving protocol inspired by discrete time crystals.

Previous demonstrations of spin state transfer in quantum dot chains relied on physical motion of electrons or sequences of SWAP operations. Here, the authors implement an alternative method based on adiabatic evolution, offering advantages in terms of implementation and robustness to noise and errors.

Maes et al. use second-order conditioning, blocking and optogenetic inhibition to show that cue-evoked dopamine transients function as temporal-difference prediction errors rather than reward predictions.

The Cancer Genome Atlas Research Network report integrated genomic and molecular analyses of 164 squamous cell carcinomas and adenocarcinomas of the oesophagus; they find genomic and molecular features that differentiate squamous and adenocarcinomas of the oesophagus, and strong similarities between oesophageal adenocarcinomas and the chromosomally unstable variant of gastric adenocarcinoma, suggesting that gastroesophageal adenocarcinoma is a single disease entity.

Evidence is found for phase-tunable Majorana zero modes in scalable two-dimensional Josephson junctions produced by top-down fabrication.

Previous work has identified several genes where mutations lead to breast cancer, but other genetic and environmental factors must still be accounted for. A large study of genetic association with breast cancer points to four novel genes and many more genetic markers that should be pursued for their link to cancer susceptibility.

Transmission of single-spin and entangled quantum states without the physical displacement of electrons is demonstrated in a quadruple quantum dot array using the Heisenberg exchange interaction and coherent SWAP gates.