Nature Search

Stimulation of protein tyrosine phosphorylation by the B-lymphocyte antigen receptor

Michael R. Gold
Debbie A. Law
Anthony L. DeFranco
Research28 Jun 1990
Nature

Volume: 345, P: 810-813
Should the uterus and ovaries be removed, and the vagina resected, routinely during radical cystectomy?

George Thalmann
Comments & Opinion01 Jan 2005
Nature Clinical Practice Urology

Volume: 2, P: 14-15
Are bladder cancer patients with pT0 disease following radical cystectomy cured of cancer?

George Thalmann
Comments & Opinion01 Oct 2006
Nature Clinical Practice Urology

Volume: 3, P: 530-531
Contemporary update on neoadjuvant therapy for bladder cancer

Nguyen and Thalmann review the benefits and disadvantages of the use of neoadjuvant chemotherapy in patients with bladder cancer, highlighting how clinical and molecular data can aid in personalizing treatment decisions, and discuss possible future application of targeted therapies and immune checkpoint inhibitors in this setting.

Daniel P. Nguyen
George N. Thalmann
Reviews14 Mar 2017
Nature Reviews Urology

Volume: 14, P: 348-358
Alterations in homologous recombination repair genes in prostate cancer brain metastases

The diagnosis of prostate cancer brain metastasis (PCBM) has increased. Here, the authors investigate the landscape of somatic genetic alterations in brain metastases in a PCBM cohort of 51 patients with non-synchronous matched primary samples available for 20 patients.

Antonio Rodriguez-Calero
John Gallon
Mark A. Rubin
ResearchOpen Access03 May 2022
Nature Communications

Volume: 13, P: 1-10
Bladder cancer organoids as a functional system to model different disease stages and therapy response

Bladder cancer heterogeneity can limit treatment efficacy in individual patients. Here, the authors use patient derived organoids to develop a drug screening pipeline and identify markers of treatment response.

Martina Minoli
Thomas Cantore
Marianna Kruithof-de Julio
ResearchOpen Access18 Apr 2023
Nature Communications

Volume: 14, P: 1-16
No survival benefit with extended lymphadenectomy: now what?

The extent of pelvic lymph node dissection at the time of radical cystectomy is debated as it might affect oncological outcomes in patients with bladder cancer. Gschwend et al. now demonstrate that the survival benefit is small and that the study might need to be repeated with a larger cohort.

Fiona C. Burkhard
George N. Thalmann
News & Views03 Dec 2018
Nature Reviews Urology

Volume: 16, P: 3-4
Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression

Transcriptional changes during prostate cancer progression are not yet fully understood. Here, the authors integrate a transcriptomics atlas of prostate cancer and validate it with preclinical models and single-cell RNA-seq, revealing the role of EZH2 and macrophage polarisation in tumour progression.

Marco Bolis
Daniela Bossi
Jean-Philippe P. Theurillat
ResearchOpen Access02 Dec 2021
Nature Communications

Volume: 12, P: 1-15
Patient-derived xenografts and organoids model therapy response in prostate cancer

To date, patients still succumb to cancer, due to tumors not responding to therapy or ultimately acquiring resistance. Here the authors show that by exploiting patient derived organoids and a treatment-naïve patient derived xenograft, patient therapy can be personalized.

Sofia Karkampouna
Federico La Manna
Marianna Kruithof-de Julio
ResearchOpen Access18 Feb 2021
Nature Communications

Volume: 12, P: 1-13
Her2 alterations in muscle-invasive bladder cancer: Patient selection beyond protein expression for targeted therapy

Bernhard Kiss
Alexander W. Wyatt
Roland Seiler
ResearchOpen Access16 Feb 2017
Scientific Reports

Volume: 7, P: 1-10
CCND1/CyclinD1 status in metastasizing bladder cancer: a prognosticator and predictor of chemotherapeutic response

Roland Seiler
George N Thalmann
Achim Fleischmann
Research26 Jul 2013
Modern Pathology

Volume: 27, P: 87-95
Differential androgen receptor signals in different cells explain why androgen-deprivation therapy of prostate cancer fails

Y Niu
T-M Chang
C Chang
Reviews03 May 2010
Oncogene

Volume: 29, P: 3593-3604
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors

Alessandro Alaimo
Marco Lorenzoni
Andrea Lunardi
ResearchOpen Access07 Dec 2020
Cell Death & Disease

Volume: 11, P: 1-17
A NF-ĸB-Activin A signaling axis enhances prostate cancer metastasis

Lanpeng Chen
Marta De Menna
B. Ewa Snaar-Jagalska
Research18 Nov 2019
Oncogene

Volume: 39, P: 1634-1651
Polygenic risk scores across the extended psychosis spectrum

Lukasz Smigielski
Sergi Papiol
Edna Grünblatt
ResearchOpen Access26 Nov 2021
Translational Psychiatry

Volume: 11, P: 1-11

Search

Stimulation of protein tyrosine phosphorylation by the B-lymphocyte antigen receptor

Should the uterus and ovaries be removed, and the vagina resected, routinely during radical cystectomy?

Are bladder cancer patients with pT0 disease following radical cystectomy cured of cancer?

Contemporary update on neoadjuvant therapy for bladder cancer

Alterations in homologous recombination repair genes in prostate cancer brain metastases

Bladder cancer organoids as a functional system to model different disease stages and therapy response

No survival benefit with extended lymphadenectomy: now what?

Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression

Patient-derived xenografts and organoids model therapy response in prostate cancer

Her2 alterations in muscle-invasive bladder cancer: Patient selection beyond protein expression for targeted therapy

CCND1/CyclinD1 status in metastasizing bladder cancer: a prognosticator and predictor of chemotherapeutic response

Differential androgen receptor signals in different cells explain why androgen-deprivation therapy of prostate cancer fails

Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors

A NF-ĸB-Activin A signaling axis enhances prostate cancer metastasis

Polygenic risk scores across the extended psychosis spectrum

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