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Advanced filters: Author: Georgios Daniil Clear advanced filters

A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism

A gain-of-function mutation in the CLCN2 chloride channel gene (encoding ClC-2) causes primary aldosteronism. The mutation abolishes voltage-dependent gating of ClC-2, highlighting a role for chloride conduction in regulating aldosterone biosynthesis.

Fabio L. Fernandes-Rosa
Georgios Daniil
Maria-Christina Zennaro
Research05 Feb 2018
Nature Genetics

Volume: 50, P: 355-361
Self-perceived quality of sleep among COPD patients in Greece: the SLEPICO study

Nikolaos Koulouris
Katerina Dimakou
Konstantinos Kostikas
ResearchOpen Access11 Jan 2022
Scientific Reports

Volume: 12, P: 1-10

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A gain-of-function mutation in the CLCN2 chloride channel gene causes primary aldosteronism

Self-perceived quality of sleep among COPD patients in Greece: the SLEPICO study

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