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Showing 1–6 of 6 results
Advanced filters: Author: Gerold Schubiger Clear advanced filters

  • This technique, adapted from mosaic analysis with double markers in mice, relies on mitotic recombination to reconstitute sequences encoding EGFP or mRFP1. After cell division, each daughter cell contains one fluorescent marker, causing a green and a red twin spot that can be traced through development.

    • Ruth Griffin
    • Anne Sustar
    • Norbert Perrimon
    Research
    Nature Methods
    Volume: 6, P: 600-602

  • Both genetic and physiological studies are contributing to our understanding of insect body size, a trait that affects fitness in many ways and is therefore subject to intense selection. Many of the genes that determine body size in insects have similar roles in mammals.

    • Bruce A. Edgar
    Reviews
    Nature Reviews Genetics
    Volume: 7, P: 907-916

  • Intense research has led to the discovery and characterization of a novel signalling network, the Hippo pathway, which is involved in growth control inDrosophila melanogaster. The importance of this pathway is emphasized by its evolutionary conservation and by increasing evidence that its deregulation occurs in human tumours.

    • Leslie J. Saucedo
    • Bruce A. Edgar
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 8, P: 613-621