Patelli et al. critically evaluate the clinical utility of liquid biopsy-based circulating tumor DNA (ctDNA) analyses in colorectal cancer management. By addressing its applications across metastatic, locoregional, and early disease settings, the authors highlight both the transformative potential and current limitations of ctDNA in guiding personalized treatment decisions.
- Giorgio Patelli
- Luca Lazzari
- Silvia Marsoni
