Nature Search

Nuclear gasdermin E drives endothelin-1-induced metastatic progression independently of the pyroptosis

Celia Roman
Valentina Caprara
Rosanna Sestito
ResearchOpen Access16 Jan 2026
Cell Death & Disease

Volume: 17, P: 1-13
β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer

YAP and mutant p53 crosstalk to regulate transcriptional processes in cancers. Here, the authors show that endothelin-1 mediated activation of β-arrestin interacts with YAP to recruit mutant p53 to the TEAD/YAP complex to promote metastasis and chemoresistance in ovarian cancer.

Piera Tocci
Roberta Cianfrocca
Anna Bagnato
ResearchOpen Access19 Jul 2019
Nature Communications

Volume: 10, P: 1-15
Microscopic assessment of lymph node status in gynecological malignancies using full-field optical coherence tomography

Matteo Pavone
Laetitia Rebiere
Aïna Venkatasamy
ResearchOpen Access21 Aug 2025
Scientific Reports

Volume: 15, P: 1-9
NLR and BRCA mutational status in patients with high grade serous advanced ovarian cancer

Claudia Marchetti
Marco D’Indinosante
Anna Fagotti
ResearchOpen Access27 May 2021
Scientific Reports

Volume: 11, P: 1-8
Multicenter, randomised, open-label, non-comparative phase 2 trial on the efficacy and safety of the combination of bevacizumab and trabectedin with or without carboplatin in women with partially platinum-sensitive recurrent ovarian cancer

Nicoletta Colombo
Eleonora Zaccarelli
Maurizio D‘Incalci
ResearchOpen Access20 Sept 2019
British Journal of Cancer

Volume: 121, P: 744-750
Improving the accuracy of BRCA1/2 mutation prediction: validation of the novel country-customized IC software

Carlo Capalbo
Enrico Ricevuto
Giuseppe Giannini
Research16 Nov 2005
European Journal of Human Genetics

Volume: 14, P: 49-54
The interaction of β-arrestin1 with talin1 driven by endothelin A receptor as a feature of α5β1 integrin activation in high-grade serous ovarian cancer

Ilenia Masi
Flavia Ottavi
Laura Rosanò
ResearchOpen Access30 Jan 2023
Cell Death & Disease

Volume: 14, P: 1-14
Targeting endothelin 1 receptor-miR-200b/c-ZEB1 circuitry blunts metastatic progression in ovarian cancer

Rosanna Sestito et al. report a miR-200b/c-mediated regulatory circuit that drives ovarian cancer metastasis via the endothelin A receptor (ET_AR). They show that blockade of ET_AR increases miR-200b/c expression and subsequently reduces ZEB1 expression, thereby inhibiting further metastatic progression.

Rosanna Sestito
Roberta Cianfrocca
Anna Bagnato
ResearchOpen Access13 Nov 2020
Communications Biology

Volume: 3, P: 1-13
Assay for apoptosis using the mitochondrial probes, Rhodamine123 and 10-N-nonyl acridine orange

Cristiano Ferlini
Giovanni Scambia
Protocols06 Dec 2007
Nature Protocols

Volume: 2, P: 3111-3114
A machine-learning parsimonious multivariable predictive model of mortality risk in patients with Covid-19

Rita Murri
Jacopo Lenkowicz
Lorenzo Zileri Dal Verme
ResearchOpen Access27 Oct 2021
Scientific Reports

Volume: 11, P: 1-10
Validation of tumour-free distance as novel prognostic marker in early-stage cervical cancer: a retrospective, single-centre, cohort study

Nicolò Bizzarri
Luigi Pedone Anchora
Gabriella Ferrandina
Research14 Apr 2021
British Journal of Cancer

Volume: 125, P: 561-568
Identification and antitumor activity of a novel inhibitor of the NIMA-related kinase NEK6

Marta De Donato
Benedetta Righino
Daniela Gallo
ResearchOpen Access30 Oct 2018
Scientific Reports

Volume: 8, P: 1-13
Real-world ANASTASE study of atezolizumab+nab-paclitaxel as first-line treatment of PD-L1-positive metastatic triple-negative breast cancer

Alessandra Fabi
Luisa Carbognin
Giovanni Scambia
ResearchOpen Access08 Sept 2023
npj Breast Cancer

Volume: 9, P: 1-7
Accessible model predicts response in hormone receptor positive HER2 negative breast cancer receiving neoadjuvant chemotherapy

Luca Mastrantoni
Giovanna Garufi
Emilio Bria
ResearchOpen Access05 Feb 2025
npj Breast Cancer

Volume: 11, P: 1-13
Real life outcome analysis of breast cancer brain metastases treated with Trastuzumab Deruxtecan

Alessandra Fabi
Alessandro Rossi
Andrea Botticelli
ResearchOpen Access22 Jan 2025
npj Precision Oncology

Volume: 9, P: 1-8
A phase II randomised (calibrated design) study on the activity of the single-agent trabectedin in metastatic or locally relapsed uterine leiomyosarcoma

Angiolo Gadducci
Federica Grosso
Maurizio D’Incalci
ResearchOpen Access30 Jul 2018
British Journal of Cancer

Volume: 119, P: 565-571
Characterization of shared neoantigens landscape in Mismatch Repair Deficient Endometrial Cancer

Elisa De Paolis
Camilla Nero
Francesco Fanfani
ResearchOpen Access20 Dec 2024
npj Precision Oncology

Volume: 8, P: 1-9
Preliminary molecular evidence associating a novel BRCA1 synonymous variant with hereditary ovarian cancer syndrome

Angelo Minucci
Paola Concolino
Ettore Capoluongo
ResearchOpen Access20 Apr 2018
Human Genome Variation

Volume: 5, P: 1-4
High-resolution melting analysis coupled with next-generation sequencing as a simple tool for the identification of a novel somatic BRCA2 variant: a case report

Alessandra Costella
Rossella De Leo
Angelo Minucci
ResearchOpen Access08 Jun 2018
Human Genome Variation

Volume: 5, P: 1-4
Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability

Giuseppe Giannini
Christian Rinaldi
Alberto Gulino
Research29 Mar 2004
Oncogene

Volume: 23, P: 2640-2647
Clinical characteristics and molecular aspects of low-grade serous ovarian and peritoneal cancer: a multicenter, observational, retrospective analysis of MITO Group (MITO 22)

Lucia Musacchio
Daniela Califano
Sandro Pignata
Research22 Jul 2022
British Journal of Cancer

Volume: 127, P: 1479-1486
Computational reactive–diffusive modeling for stratification and prognosis determination of patients with breast cancer receiving Olaparib

Francesco Schettini
Maria Valeria De Bonis
Daniele Generali
ResearchOpen Access24 Jul 2023
Scientific Reports

Volume: 13, P: 1-11
Stat1 confers sensitivity to radiation in cervical cancer cells by controlling Parp1 levels: a new perspective for Parp1 inhibition

Giuseppina Raspaglio
Marianna Buttarelli
Daniela Gallo
ResearchOpen Access12 Oct 2021
Cell Death & Disease

Volume: 12, P: 1-13
Author Correction: Real-world ANASTASE study of atezolizumab+nab-paclitaxel as first-line treatment of PD-L1-positive metastatic triple-negative breast cancer

Alessandra Fabi
Luisa Carbognin
Giovanni Scambia
Amendments and CorrectionsOpen Access05 Feb 2024
npj Breast Cancer

Volume: 10, P: 1
Germline BRCA 1-2 status prediction through ovarian ultrasound images radiogenomics: a hypothesis generating study (PROBE study)

Camilla Nero
Francesca Ciccarone
Giovanni Scambia
ResearchOpen Access05 Oct 2020
Scientific Reports

Volume: 10, P: 1-11
Author Correction: Real-world ANASTASE study of atezolizumab+nab-paclitaxel as first-line treatment of PD-L1-positive metastatic triple-negative breast cancer

Alessandra Fabi
Luisa Carbognin
Giovanni Scambia
Amendments and CorrectionsOpen Access30 Oct 2023
npj Breast Cancer

Volume: 9, P: 1
Author Correction: The interaction of β-arrestin1 with talin1 driven by endothelin A receptor as a feature of α5β1 integrin activation in high-grade serous ovarian cancer

Ilenia Masi
Flavia Ottavi
Laura Rosanò
Amendments and CorrectionsOpen Access21 Oct 2024
Cell Death & Disease

Volume: 15, P: 1-2
Prognostic role of topoisomerase-IIα in advanced ovarian cancer patients

G Ferrandina
M Petrillo
G Scambia
ResearchOpen Access27 May 2008
British Journal of Cancer

Volume: 98, P: 1910-1915
A multicentre phase II study of carboplatin plus pegylated liposomal doxorubicin as first-line chemotherapy for patients with advanced or recurrent endometrial carcinoma: the END-1 study of the MITO (Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies) group

S Pignata
G Scambia
F Perrone
ResearchOpen Access08 May 2007
British Journal of Cancer

Volume: 96, P: 1639-1643
Phase II study of liposomal doxorubicin and gemcitabine in the salvage treatment of ovarian cancer

G D'Agostino
G Ferrandina
G Scambia
ResearchOpen Access30 Sept 2003
British Journal of Cancer

Volume: 89, P: 1180-1184
Spot-light on microbiota in obesity and cancer

Paolo Marzullo
Silvia Bettini
Giuseppe Bifulco
Reviews06 Aug 2021
International Journal of Obesity

Volume: 45, P: 2291-2299

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