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Showing 1–3 of 3 results
Advanced filters: Author: Gisel E. Peña Murillo Clear advanced filters

  • The main protease, a key enzyme of SARS-CoV-2, can protect itself from oxidative damage. Here, Reinke, Schubert, and colleagues used XFEL radiation to image the enzyme, revealing the disulfide and NOS/SONOS bonds that form in response to oxygen.

    • Patrick Y. A. Reinke
    • Robin Schubert
    • Thomas J. Lane
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-10

  • Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it.

    • Susannah Holmes
    • Henry J. Kirkwood
    • Connie Darmanin
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • There is a need for more robust sample delivery methods for serial crystallography. Here the authors present the design and characterization of ultracompact 3D microfluidic devices that can be printed, which require less sample, have a lower background signal and allow 3D mixing for time resolved experiments.

    • Juraj Knoška
    • Luigi Adriano
    • Michael Heymann
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12