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Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIβ at the Golgi complex

Angelika Hausser
Peter Storz
Klaus Pfizenmaier
Research14 Aug 2005
Nature Cell Biology

Volume: 7, P: 880-886
Broadly conserved FlgV controls flagellar assembly and Borrelia burgdorferi dissemination in mice

The control of flagellar synthesis and function in the Lyme spirochete Borrelia burgdorferi is poorly understood, as this pathogen lacks the typical flagellar sigma factor and transcriptional regulators. Here, the authors identify a broadly conserved structural flagellar component that modulates flagellar assembly and is important for cell division, motility and virulence.

Maxime Zamba-Campero
Daniel Soliman
Philip P. Adams
ResearchOpen Access29 Nov 2024
Nature Communications

Volume: 15, P: 1-21
P-type ATPase magnesium transporter MgtA acts as a dimer

Zeinert et al. provide cryo-EM structures of the E. coli Mg²⁺ importer MgtA: unexpectedly, this P-type ATPase is a dimer with an uncommon transmembrane ion-binding site and knotted N-terminus, which are functionally important features.

Rilee Zeinert
Fei Zhou
Doreen Matthies
Research23 Jun 2025
Nature Structural & Molecular Biology

Volume: 32, P: 1633-1643
Extensive diversity in RNA termination and regulation revealed by transcriptome mapping for the Lyme pathogen Borrelia burgdorferi

Transcription termination can tune bacterial gene expression in response to diverse signals. Here, the authors use several RNA-seq approaches to map RNA ends for the transcriptome of the spirochete Borrelia burgdorferi, providing insights into various modes of transcription termination and identifying potential RNA regulators in this pathogen.

Emily Petroni
Caroline Esnault
Philip P. Adams
ResearchOpen Access04 Jul 2023
Nature Communications

Volume: 14, P: 1-23
Structural basis for redox regulation of Yap1 transcription factor localization

Matthew J. Wood
Gisela Storz
Nico Tjandra
Research19 Aug 2004
Nature

Volume: 430, P: 917-921
An RNA sponge controls quorum sensing dynamics and biofilm formation in Vibrio cholerae

Small regulatory RNAs (sRNAs) often act in concert with the RNA-chaperone Hfq to regulate the expression of multiple target transcripts in bacteria. Here, the authors identify Hfq-interacting sRNAs and their targets in the pathogen Vibrio cholerae, including an RNA sponge that binds and inactivates four sRNAs that modulate the quorum sensing pathway.

Michaela Huber
Anne Lippegaus
Kai Papenfort
ResearchOpen Access08 Dec 2022
Nature Communications

Volume: 13, P: 1-14
Small RNA with a large impact

A simultaneous comparison of the RNA molecules expressed by Salmonella bacteria and human cells during infection reveals how a bacterial small RNA alters the transcript profiles of both the bacteria and the host cells. See Article p.496

Matthias P. Machner
Gisela Storz
News & Views20 Jan 2016
Nature

Volume: 529, P: 472-473
Publisher Correction: Definitions and guidelines for research on antibiotic persistence

Nathalie Q. Balaban
Sophie Helaine
Annelies Zinkernagel
Amendments and Corrections29 Apr 2019
Nature Reviews Microbiology

Volume: 17, P: 460
Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction path

Cheolju Lee
Soon Mi Lee
Seong Eon Ryu
Research14 Nov 2004
Nature Structural & Molecular Biology

Volume: 11, P: 1179-1185
Definitions and guidelines for research on antibiotic persistence

Antibiotic persistence contributes to the survival of bacteria during antibiotic treatment. In this Consensus Statement, scientists working on the response of bacteria to antibiotics define antibiotic persistence and provide practical guidance on how to study bacterial persisters.

Nathalie Q. Balaban
Sophie Helaine
Annelies Zinkernagel
ReviewsOpen Access12 Apr 2019
Nature Reviews Microbiology

Volume: 17, P: 441-448
ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis

Reactive oxygen species (ROS) have been shown to be toxic but also function as signalling molecules. Recent studies have provided insights into the mechanisms that regulate ROS homeostasis and provide specificity in ROS signalling from prokaryotes to mammals.

Benoît D'Autréaux
Michel B. Toledano
Reviews01 Oct 2007
Nature Reviews Molecular Cell Biology

Volume: 8, P: 813-824

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Protein kinase D regulates vesicular transport by phosphorylating and activating phosphatidylinositol-4 kinase IIIβ at the Golgi complex

Broadly conserved FlgV controls flagellar assembly and Borrelia burgdorferi dissemination in mice

P-type ATPase magnesium transporter MgtA acts as a dimer

Extensive diversity in RNA termination and regulation revealed by transcriptome mapping for the Lyme pathogen Borrelia burgdorferi

Structural basis for redox regulation of Yap1 transcription factor localization

An RNA sponge controls quorum sensing dynamics and biofilm formation in Vibrio cholerae

Small RNA with a large impact

Publisher Correction: Definitions and guidelines for research on antibiotic persistence

Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction path

Definitions and guidelines for research on antibiotic persistence

ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis

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