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Showing 1–3 of 3 results
Advanced filters: Author: Gist Croft Clear advanced filters

  • An in vitro model to study the early events that direct human embryo development after formation of the blastocyst and implantation in the uterine wall.

    • Alessia Deglincerti
    • Gist F. Croft
    • Ali H. Brivanlou
    Research
    Nature
    Volume: 533, P: 251-254

  • Previous work has suggested that induced pluripotent stem cells (iPSCs) are inferior to embryonic stem cells (ESCs) with respect to in vitro differentiation, raising questions about the utility of iPSCs for disease modeling. Characterization of a test set of 16 human iPSC lines shows that they perform as well as ESCs in differentiating to motor neurons.

    • Gabriella L Boulting
    • Evangelos Kiskinis
    • Kevin Eggan
    Research
    Nature Biotechnology
    Volume: 29, P: 279-286

  • Simunovic et al. use human embryonic stem cells to generate a three-dimensional model of a human pre-gastrulation epiblast and show that anterior–posterior symmetry breaking can be induced by BMP4 and WNT signalling.

    • Mijo Simunovic
    • Jakob J. Metzger
    • Eric D. Siggia
    Research
    Nature Cell Biology
    Volume: 21, P: 900-910