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Showing 1–4 of 4 results

Advanced filters: Author: Giyoung Jung Clear advanced filters

Circuit-guided population acclimation of a synthetic microbial consortium for improved biochemical production

Achieving stable production by co-culturing multiple microorganisms is often challenging due to difficulties in controlling its population. Here, the authors develop a “population guider” that can acclimate a population to higher production.

Chae Won Kang
Hyun Gyu Lim
Gyoo Yeol Jung
ResearchOpen Access07 Nov 2022
Nature Communications

Volume: 13, P: 1-9
Small-molecule control of antibody N-glycosylation in engineered mammalian cells

Synthetic gene circuits regulated by small molecules have been used to fine-tune glycosyltransferase expression in CHO cells, providing a method to produce therapeutic monoclonal antibodies with precise glycosylation states.

Michelle M. Chang
Leonid Gaidukov
Ron Weiss
Research20 May 2019
Nature Chemical Biology

Volume: 15, P: 730-736
Sensitive fluorescence detection of SARS-CoV-2 RNA in clinical samples via one-pot isothermal ligation and transcription

A one-pot enzymatic assay for the fluorescence detection of RNA accurately and rapidly detects specific viral and bacterial pathogens, as shown for SARS-CoV-2 RNA in clinical samples.

Chang Ha Woo
Sungho Jang
Jeong Wook Lee
Research18 Sept 2020
Nature Biomedical Engineering

Volume: 4, P: 1168-1179
Optical High Content Nanoscopy of Epigenetic Marks Decodes Phenotypic Divergence in Stem Cells

Joseph J. Kim
Neal K. Bennett
Prabhas V. Moghe
ResearchOpen Access04 Jan 2017
Scientific Reports

Volume: 7, P: 1-15