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Showing 1–3 of 3 results
Advanced filters: Author: Grit Walther Clear advanced filters

  • Epimutations mediated by RNA interference can confer antifungal drug resistance and affect virulence in fungi. Here, the authors show that these epigenetic modifications can be transmitted across generations following sexual reproduction in a pathogenic fungus.

    • Carlos Pérez-Arques
    • María Isabel Navarro-Mendoza
    • Joseph Heitman
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11

  • The de novo genome assembly and analysis of 300 Aspergillus fumigatus genomes from environmental and clinical isolates provides insight into the pan-genome of this important human fungal pathogen. Genome-wide association studies identify genomic variation associated with human infection and triazole resistance, and reveal potential therapeutic antifungal targets.

    • Amelia E. Barber
    • Tongta Sae-Ong
    • Oliver Kurzai
    Research
    Nature Microbiology
    Volume: 6, P: 1526-1536