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Low dose IL-2 therapy restores regulatory T cells in patients with systemic lupus erythematosus in a dose-dependent manner: a phase IIb trial

Low-dose IL-2 therapy has been evaluated for the treatment of numerous autoimmune conditions. This study reports the outcomes of a phase 2, randomised, placebo-controlled trial evaluating the efficacy and safety of low-dose IL-2 for the treatment of systemic lupus erythematosus (SLE).

Xia Zhang
Ruiling Feng
Jing He
ResearchOpen Access21 Apr 2026
Nature Communications

P: 1-10
Edoxaban for stroke prevention in atrial fibrillation and factors associated with dosing: patient characteristics from the prospective observational ETNA-AF-China registry

Xueyuan Guo
Juan Du
Jian Zhang
ResearchOpen Access02 Feb 2024
Scientific Reports

Volume: 14, P: 1-15
Cellular basis of enhanced humoral immunity to SARS-CoV-2 upon homologous or heterologous booster vaccination analyzed by single-cell immune profiling

Jingwen Ai
Jingxin Guo
Wenhong Zhang
ResearchOpen Access21 Oct 2022
Cell Discovery

Volume: 8, P: 1-15

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