Nature Search

A male-essential miRNA is key for avian sex chromosome dosage compensation

Birds have evolved a unique sex chromosome dosage compensation mechanism involving the male-biased microRNA (miR-2954), which is essential for male survival by regulating the expression of dosage-sensitive Z-linked genes.

Amir Fallahshahroudi
Sara Yousefi Taemeh
Henrik Kaessmann
ResearchOpen Access16 Jul 2025
Nature

Volume: 645, P: 148-157
Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue

Bacterial MutS2, a paralogue of the DNA mismatch-repair protein MutS, is found to bind collided ribosomes and function in translational quality control.

Federico Cerullo
Sebastian Filbeck
Claudio A. P. Joazeiro
Research09 Mar 2022
Nature

Volume: 603, P: 509-514
SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface

Antibodies targeting the spike protein of coronaviruses are potential candidates for therapeutic development. Here, Bertoglio et al. use phage display to select anti-SARS-CoV-2 spike antibodies from the human naïve universal antibody gene libraries HAL9/10 that block interaction with ACE2 receptor to inhibit infection.

Federico Bertoglio
Doris Meier
Michael Hust
ResearchOpen Access11 Mar 2021
Nature Communications

Volume: 12, P: 1-15
HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer

N Stojanovic
Z Hassan
G Schneider
Research10 Oct 2016
Oncogene

Volume: 36, P: 1804-1815
MTOR inhibitor-based combination therapies for pancreatic cancer

Zonera Hassan
Christian Schneeweis
Günter Schneider
ResearchOpen Access02 Jan 2018
British Journal of Cancer

Volume: 118, P: 366-377

Quick links

Search

Filter By:

A male-essential miRNA is key for avian sex chromosome dosage compensation

Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue

SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface

HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer

MTOR inhibitor-based combination therapies for pancreatic cancer

Search

Quick links