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Showing 1–2 of 2 results
Advanced filters: Author: Guiting Zhan Clear advanced filters
  • Photothermal therapy (PTT) has emerged as a promising approach for cancer treatment. Here, in preclinical cancer models, the authors show that PTT efficacy could be improved using tumor cell-derived microparticles that co-deliver the photosensitizer indocyanine green and a vitamin-D receptor ligand, calcipotriol, resulting in tumor extracellular matrix remodelling and ameliorated anti-tumor immune responses.

    • Xin Li
    • Tuying Yong
    • Xiangliang Yang
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-19
  • Durable response rate to anti-PD-1/PD-L1 therapy remains relatively low in patients with cancer. Here the authors show that metformin-loaded mannose-modified macrophage-derived microparticles reprogram the tumor immune microenvironment and improve responses to anti-PD-1 therapy.

    • Zhaohan Wei
    • Xiaoqiong Zhang
    • Xiangliang Yang
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-20