Nature Search

Reflections on a peptide

Leo Brady
Guy Dodson
News & Views21 Apr 1994
Nature

Volume: 368, P: 692-693
Prostaglandin Production and Zinc Depletion in Human Pregnancy

Karen Simmer
Neville A Punchard
Richard P H Thompson
Research01 Jul 1985
Pediatric Research

Volume: 19, P: 697-700
Unravelling the mechanism of neurotensin recognition by neurotensin receptor 1

GPCRs include inactive and active states. ¹⁹F-NMR and stopped-flow fluorescence kinetic assays reveal that neurotensin activates the prototypical peptide-binding GPCR, neurotensin receptor 1, through an induced-fit mechanism, where ligand binding precedes receptor conformational changes.

Kazem Asadollahi
Sunnia Rajput
Paul R. Gooley
ResearchOpen Access09 Dec 2023
Nature Communications

Volume: 14, P: 1-13
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

Martin Tobin and colleagues report a meta-analysis of 23 genome-wide association studies for pulmonary function. They identify 16 loci newly associated with variation in two cross-sectional measures of lung function, used to define airway obstruction and to grade the severity of obstruction.

María Soler Artigas
Daan W Loth
Martin D Tobin
Research25 Sept 2011
Nature Genetics

Volume: 43, P: 1082-1090
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab

Vaccination is effective in protecting from COVID-19. Here the authors report immune responses and breakthrough infections in twice-vaccinated patients receiving anti-TNF treatments for inflammatory bowel disease, and find dampened vaccine responses that implicate the need of adapted vaccination schedules for these patients.

Simeng Lin
Nicholas A. Kennedy
Jeannie Bishop
ResearchOpen Access16 Mar 2022
Nature Communications

Volume: 13, P: 1-14
SKOR1 has a transcriptional regulatory role on genes involved in pathways related to restless legs syndrome

Faezeh Sarayloo
Dan Spiegelman
Guy A. Rouleau
Research22 Jun 2020
European Journal of Human Genetics

Volume: 28, P: 1520-1528
Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy

It remains critical to understand the genomic events in response to treatment of oesophageal adenocarcinoma (OAC). Here, the authors perform a multi-omics analysis of OAC patients from the DOCTOR phase II clinical trial, finding genomic features and immune clusters associated with survival.

Marjan M. Naeini
Felicity Newell
Nicola Waddell
ResearchOpen Access31 May 2023
Nature Communications

Volume: 14, P: 1-17
Elevated levels of the stress hormone, corticosterone, cause ‘pessimistic’ judgment bias in broiler chickens

Oluwaseun S. Iyasere
Andrew P. Beard
Melissa Bateson
ResearchOpen Access31 Jul 2017
Scientific Reports

Volume: 7, P: 1-12
A motif in the αβ T-cell receptor controls positive selection by modulating ERK activity

Guy Werlen
Barbara Hausmann
Ed Palmer
Research27 Jul 2000
Nature

Volume: 406, P: 422-426
Dynamic control of neurochemical release with ultrasonically-sensitive nanoshell-tethered liposomes

Nanoscale materials hold promising applications for controlled release of bioactive compounds. Here hollow gold nanoshells tethered to liposomes allows the controlled release of encapsulated neurochemicals by acoustic or laser stimulation

Sean M. Mackay
David Mo Aung Myint
Eng Wui Tan
ResearchOpen Access25 Oct 2019
Communications Chemistry

Volume: 2, P: 1-10

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