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British Journal of Cancer (7)
Cell Death & Disease (5)
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Showing 1–21 of 21 results

Advanced filters: Author: H Kashkar Clear advanced filters

Elevated XIAP expression alone does not confer chemoresistance

J M Seeger
K Brinkmann
H Kashkar
ResearchOpen Access18 May 2010
British Journal of Cancer

Volume: 102, P: 1717-1723
Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis

M Hörnle
N Peters
D Kulms
Research20 Sept 2010
Oncogene

Volume: 30, P: 575-587
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth

During angiogenesis the vasculature switches from a quiescent to a proliferative state. Here the authors show that mitochondrial respiration in endothelial cells controls angiogenesis during development, tumour growth and tissue repair.

L. M. Schiffmann
J. P. Werthenbach
H. Kashkar
ResearchOpen Access21 Jul 2020
Nature Communications

Volume: 11, P: 1-13
Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

The enzymatic activity of caspase-8 controls apoptosis, necroptosis and pyroptosis, and prevents tissue damage during embryonic development and adulthood in mice.

Melanie Fritsch
Saskia D. Günther
Hamid Kashkar
Research20 Nov 2019
Nature

Volume: 575, P: 683-687
Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through lipopolysaccharide

The lipopolysaccharide of the intracellular pathogen Shigella, in particular its O antigen, interacts with caspases and blocks their activation to prevent apoptosis.

Saskia D. Günther
Melanie Fritsch
Hamid Kashkar
Research23 Dec 2019
Nature Microbiology

Volume: 5, P: 354-367
Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP

J Cummings
T H Ward
C Dive
ResearchOpen Access01 Feb 2005
British Journal of Cancer

Volume: 92, P: 532-538
CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage

Marie-Christine Albert
Kerstin Brinkmann
Hamid Kashkar
ResearchOpen Access10 Sept 2020
Cell Death & Disease

Volume: 11, P: 1-15
Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib

D Lecis
C Drago
D Delia
ResearchOpen Access11 May 2010
British Journal of Cancer

Volume: 102, P: 1707-1716
Identification of serum angiopoietin-2 as a biomarker for clinical outcome of colorectal cancer patients treated with bevacizumab-containing therapy

V Goede
O Coutelle
U T Hacker
ResearchOpen Access05 Oct 2010
British Journal of Cancer

Volume: 103, P: 1407-1414
Ceramide and raft signaling are linked with each other in UVA radiation-induced gene expression

S Grether-Beck
M Salahshour-Fard
J Krutmann
Research28 Apr 2008
Oncogene

Volume: 27, P: 4768-4778
Bortezomib sensitises TRAIL-resistant HPV-positive head and neck cancer cells to TRAIL through a caspase-dependent, E6-independent mechanism

J Bullenkamp
N Raulf
M Tavassoli
ResearchOpen Access23 Oct 2014
Cell Death & Disease

Volume: 5, P: e1489
Defective Bax activation in Hodgkin B-cell lines confers resistance to staurosporine-induced apoptosis

H Kashkar
M Krönke
J M Jürgensmeier
Research12 Jun 2002
Cell Death & Differentiation

Volume: 9, P: 750-757
Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6

S Schüll
S D Günther
H Kashkar
ResearchOpen Access12 Mar 2015
Cell Death & Disease

Volume: 6, P: e1691
Dual targeting of Angiopoetin-2 and VEGF potentiates effective vascular normalisation without inducing empty basement membrane sleeves in xenograft tumours

O Coutelle
L M Schiffmann
U T Hacker
ResearchOpen Access06 Jan 2015
British Journal of Cancer

Volume: 112, P: 495-503
Dying in self-defence: a comparative overview of immunogenic cell death signalling in animals and plants

Takaki Maekawa
Hamid Kashkar
Núria S. Coll
ReviewsOpen Access04 Oct 2022
Cell Death & Differentiation

Volume: 30, P: 258-268
Hypoxia-induced p38 MAPK activation reduces Mcl-1 expression and facilitates sensitivity towards BH3 mimetics in chronic lymphocytic leukemia

M F Huelsemann
M Patz
L P Frenzel
Correspondence07 Nov 2014
Leukemia

Volume: 29, P: 981-984
S-palmitoylation represents a novel mechanism regulating the mitochondrial targeting of BAX and initiation of apoptosis

M Fröhlich
B Dejanovic
S Nussberger
ResearchOpen Access13 Feb 2014
Cell Death & Disease

Volume: 5, P: e1057
Targeting the mitochondrial apoptotic pathway: a preferred approach in hematologic malignancies?

K Brinkmann
H Kashkar
ReviewsOpen Access06 Mar 2014
Cell Death & Disease

Volume: 5, P: e1098
TNF-receptor-1 adaptor protein FAN mediates TNF-induced B16 melanoma motility and invasion

A Boecke
A C Carstens
M Krönke
ResearchOpen Access14 May 2013
British Journal of Cancer

Volume: 109, P: 422-432
A combination of low-dose bevacizumab and imatinib enhances vascular normalisation without inducing extracellular matrix deposition

L M Schiffmann
M Brunold
O Coutelle
ResearchOpen Access31 Jan 2017
British Journal of Cancer

Volume: 116, P: 600-608
Apoptotic cell death in disease—Current understanding of the NCCD 2023

Ilio Vitale
Federico Pietrocola
Lorenzo Galluzzi
Reviews26 Apr 2023
Cell Death & Differentiation

Volume: 30, P: 1097-1154