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Showing 1–50 of 111 results

Advanced filters: Author: H Toyoshima Clear advanced filters

Oxygen production from chlorophyll-liposomes

W. STILLWELL
H. TI TIEN
Research01 Jun 1978
Nature

Volume: 273, P: 406
Energy flow and the number of trophic levels in ecological communities

D. L. DEANGELIS
R. H. GARDNER
J. H. CARNEY
Research01 Jun 1978
Nature

Volume: 273, P: 406-407
Pumping ions

An influx of calcium ions into the cytoplasm activates a variety of cellular processes. The Ca²⁺ concentration is then returned to sub-micromolar levels by an ATP-driven Ca²⁺pump. The first high-resolution structure of such a pump reveals in exquisite detail the structural features that may underlie the pump's activity.

David H. MacLennan
N. Michael Green
News & Views08 Jun 2000
Nature

Volume: 405, P: 633-634
Regulation of Ca²⁺ -dependent K⁺ -channel activity in tracheal myocytes by phosphorylation

H. Kume
A. Takai
T. Tomita
Research14 Sept 1989
Nature

Volume: 341, P: 152-154
Calcium callisthenics

The Ca²⁺-ATPase is one of the best characterized of the pumps that move ions across cell membranes. The latest snapshot of the pump in another of its many conformations is a major step in understanding its dynamics.

N. Michael Green
David H. MacLennan
News & Views08 Aug 2002
Nature

Volume: 418, P: 598-599
Cis–trans isomerisation in rhodopsin occurs in picoseconds

B. H. GREEN
T. G. MONGER
R. H. CALLENDER
Research01 Sept 1977
Nature

Volume: 269, P: 179-180
Rat platelets aggregate in the absence of endogenous precursors of prostaglandin endoperoxides

H. BULT
I. L. BONTA
Research02 Dec 1976
Nature

Volume: 264, P: 449-451
Inactivation of p27^Kip1 by the viral E1A oncoprotein in TGFβ-treated cells

Asoke Mal
Randy Y. C. Poon
Marian L. Harter
Research21 Mar 1996
Nature

Volume: 380, P: 262-265
Photo-oxidation of water in phospholipid bilayer membranes containing chlorophyll a

Y. TOYOSHIMA
M. MORINO
M. SUKIGARA
Research01 Jan 1977
Nature

Volume: 265, P: 187-189
Post-transcriptional control of avian oncornavirus transforming gene sequences in mammalian cells

RICHARD A. KRZYZEK
ALAN F. LAU
DEBORAH H. SPECTOR
Research01 Sept 1977
Nature

Volume: 269, P: 175-179
Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis

TANK binding kinase 1 (TBK1) is a non-canonical IκB kinase that regulates immunity via NF-κB. Here Pillai et al. show that TBK1 localizes to centrosomes during mitosis, and regulates microtubule dynamics and spindle formation by phosphorylating the centrosomal protein CEP170 and the mitotic apparatus protein NuMa.

Smitha Pillai
Jonathan Nguyen
Srikumar Chellappan
ResearchOpen Access10 Dec 2015
Nature Communications

Volume: 6, P: 1-14
A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

Dionisio Martin-Zanca
Stephen H. Hughes
Mariano Barbacid
Research27 Feb 1986
Nature

Volume: 319, P: 743-748
Occurrence of the 3.3-µm feature in galaxies

T. J. Lee
D. H. Beattie
A. R. Hyland
Research21 Jan 1982
Nature

Volume: 295, P: 214-215
Prognostic role of p27^Kip1 and apoptosis in human breast cancer

J Wu
Z-Z Shen
Z-M Shao
ResearchOpen Access26 Feb 1999
British Journal of Cancer

Volume: 79, P: 1572-1578
Prognostic significance of Helix pomatia lectin and c-erbB-2 oncoprotein in human breast cancer

M Thomas
M Noguchi
I Miyazaki
Research01 Sept 1993
British Journal of Cancer

Volume: 68, P: 621-626
Nucleotide sequence of avian retroviral oncogene v-mil: homologue of murine retroviral oncogene v-raf

P. Sutrave
T. I. Bonner
K. Bister
Research03 May 1984
Nature

Volume: 309, P: 85-88
Specific detection of c-erbB-2 mRNA expression in gastric cancers by the polymerase chain reaction following reverse transcription

I Ninomiya
Y Endo
T Sasaki
Research01 Jul 1992
British Journal of Cancer

Volume: 66, P: 84-87
Prolonged survival of mice with human gastric cancer treated with an anti-c-ErbB-2 monoclonal antibody

Y Ohnishi
H Nakamura
K Shimamura
Research01 May 1995
British Journal of Cancer

Volume: 71, P: 969-973
Homology between phosphotyrosine acceptor site of human c-abl and viral oncogene products

John Groffen
Nora Heisterkamp
John R. Stephenson
Research14 Jul 1983
Nature

Volume: 304, P: 167-169
Dependence on pH of polarized sorting of secreted proteins

Michael J. Caplan
Jennifer L. Stow
James D. Jamieson
Research21 Oct 1987
Nature

Volume: 329, P: 632-635
Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

Birgit Millauer
Laura K. Shawver
Axel Ullrich
Research10 Feb 1994
Nature

Volume: 367, P: 576-579
Inflation and shadow matter

Lawrence M. Krauss
Alan H. Guth
William H. Press
Research27 Feb 1986
Nature

Volume: 319, P: 748-751
Structural evidence that myosin heads may interact with two sites on F-actin

L. A. Amos
H. E. Huxley
K. A. Taylor
Research30 Sept 1982
Nature

Volume: 299, P: 467-469
Enforced CDK4 expression in a hematopoietic cell line confers resistance to the G1 arrest induced by ionizing radiation

Michael F Reed
Vivian F Liu
Mark E Ewen
Research09 Dec 1998
Oncogene

Volume: 17, P: 2961-2971
Differential effects of transforming growth factor on cell cycle regulatory molecules in human myeloid leukemia cells

Xiaotang Hu
Xiaohong Zhang
Kenneth S Zuckerman
Research25 Oct 2001
Oncogene

Volume: 20, P: 6840-6850
c-erbB-2 in astrocytomas: infrequent overexpression by immunohistochemistry and absence of gene amplification by fluorescence in situ hybridization

H Haapasalo
E Hyytinen
J Isola
Research01 Mar 1996
British Journal of Cancer

Volume: 73, P: 620-623
Molecular analysis of p21 and p27 genes in human pituitary adenomas

H Ikeda
T Yoshimoto
N Shida
Research01 Nov 1997
British Journal of Cancer

Volume: 76, P: 1119-1123
Cystic Fibrosis. I. Fractionation of the Mucociliary Inhibitor from Plasma

Steven D Carson
Barbara H Bowman
Research01 Jan 1982
Pediatric Research

Volume: 16, P: 13-20
Cell cycle arrest and DNA endoreduplication following p21^Waf1/Cip1 expression

Stewart Bates
Kevin M Ryan
Karen H Vousden
Research01 Oct 1998
Oncogene

Volume: 17, P: 1691-1703
Decreasing of p27^Kip1 and cyclin E protein levels is associated with progression from superficial into invasive bladder cancer

T Kamai
K Takagi
K-I Yoshida
ResearchOpen Access01 May 2001
British Journal of Cancer

Volume: 84, P: 1242-1251
Correction: Light-emitting diodes based on conjugated polymers

J. H. Burroughes
D. D. C. Bradley
A. B. Holmes
Amendments and Corrections22 Nov 1990
Nature

Volume: 348, P: 352
Antenatal magnesium sulfate and the postnatal response of the ductus arteriosus to indomethacin in extremely preterm neonates

Y Katayama
H Minami
Y K Lee
Research27 May 2010
Journal of Perinatology

Volume: 31, P: 21-24
Phospholamban: a crucial regulator of cardiac contractility

David H. MacLennan
Evangelia G. Kranias
Reviews01 Jul 2003
Nature Reviews Molecular Cell Biology

Volume: 4, P: 566-577
Individual and joint impact of family history and Helicobacter pylori infection on the risk of stomach cancer: a nested case–control study

H Yatsuya
H Toyoshima
T Yoshimura
ResearchOpen Access27 Jul 2004
British Journal of Cancer

Volume: 91, P: 929-934
A fraction unresponsive to growth inhibition by TGF-β among the high-proliferative potential progenitor cells in bone marrow of p53-deficient mice

H Sasaki
M Matsuda
T Inoue
Research01 Feb 1997
Leukemia

Volume: 11, P: 239-244
Overexpression of p21^waf1/cip1 arrests the growth of chicken embryo fibroblasts that overexpress E2F1

Iris Givol
David Givol
Stephen H Hughes
Research17 Jun 1998
Oncogene

Volume: 16, P: 3115-3122
A phase I dose escalation study of BIBW 2992, an irreversible dual inhibitor of epidermal growth factor receptor 1 (EGFR) and 2 (HER2) tyrosine kinase in a 2-week on, 2-week off schedule in patients with advanced solid tumours

F A L M Eskens
C H Mom
E G E de Vries
ResearchOpen Access20 Nov 2007
British Journal of Cancer

Volume: 98, P: 80-85
Recurrent ATP1A2 mutations in Portuguese families with familial hemiplegic migraine

Maria-José Castro
Anine H. Stam
Arn M. J. M. van den Maagdenberg
Research19 Oct 2007
Journal of Human Genetics

Volume: 52, P: 990-998
TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

Yoshimi Nakagawa
Hitoshi Shimano
Nobuhiro Yamada
Research04 Dec 2005
Nature Medicine

Volume: 12, P: 107-113
Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance

Takashi Matsuzaka
Hitoshi Shimano
Nobuhiro Yamada
Research30 Sept 2007
Nature Medicine

Volume: 13, P: 1193-1202
A prospective study of stomach cancer death in relation to green tea consumption in Japan

Y Hoshiyama
T Kawaguchi
T Yoshimura
ResearchOpen Access23 Jul 2002
British Journal of Cancer

Volume: 87, P: 309-313
Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities

Guangan He
Zahid H Siddik
Jian Kuang
Research07 Feb 2005
Oncogene

Volume: 24, P: 2929-2943
Role of Gadd45α in the density-dependent G1 arrest induced by p27^Kip1

Xiaohong Zhang
Le Ma
W J Pledger
Research02 Jul 2003
Oncogene

Volume: 22, P: 4166-4174
No concomitant occurrence of the N-ras and p53 gene mutations in myelodysplastic syndromes

K Mitani
A Hangaishi
H Hirai
Research01 Jun 1997
Leukemia

Volume: 11, P: 863-865
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
An inbred colony of oncogene transgenic mice: diversity of tumours and potential as a therapeutic model

H Thomas
AM Hanby
FR Balkwill
Research01 Jan 1996
British Journal of Cancer

Volume: 73, P: 65-72
In vitro genetic screen identifies a cooperative role for LPA signaling and c-Myc in cell transformation

P Taghavi
E Verhoeven
M van Lohuizen
Research01 Sept 2008
Oncogene

Volume: 27, P: 6806-6816
p21 provides stage specific DNA damage control to preimplantation embryos

S K Adiga
M Toyoshima
O Niwa
Research09 Apr 2007
Oncogene

Volume: 26, P: 6141-6149
Getting in and out of mitosis with Polo-like kinase-1

Marcel A T M van Vugt
René H Medema
Reviews18 Apr 2005
Oncogene

Volume: 24, P: 2844-2859
Production of matrix metalloproteinase 9 (92-kDa gelatinase) by human oesophageal squamous cell carcinoma in response to epidermal growth factor

I Shima
Y Sasaguri
M Morimatsu
Research01 Apr 1993
British Journal of Cancer

Volume: 67, P: 721-727

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