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Showing 1–50 of 787 results

Advanced filters: Author: H. Fuchs Clear advanced filters

Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy

Fuchs endothelial corneal dystrophy (FECD) is one of the most common reasons for corneal transplantation, and is known to cluster in families. Here, the authors discover new genetic loci associated with FECD with sex-specific effects and implications for disease mechanism.

Natalie A. Afshari
Robert P. Igo Jr
Sudha K. Iyengar
ResearchOpen Access30 Mar 2017
Nature Communications

Volume: 8, P: 1-8
Cataract surgery with introcular lens implantation in Fuchs' Heterochromic Cyclitis

C M Jakeman
K Jordan
S Perry
Research01 Jul 1990
Eye

Volume: 4, P: 543-547
A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation

A multi-ancestry GWAS meta-analysis of Fuchs endothelial corneal dystrophy identifies eight novel loci, including low-frequency missense variants in laminin genes LAMA5 and LAMB1, and phenome-wide scans uncover pleiotropy with renal traits at TCF4.

Bryan R. Gorman
Michael Francis
Sudha K. Iyengar
ResearchOpen Access06 Apr 2024
Communications Biology

Volume: 7, P: 1-12
Aqueous flare and cells in Fuchs syndrome

W Fang
H Zhou
A Kijlstra,
Research26 Oct 2007
Eye

Volume: 23, P: 79-84
Cellular and subbasal nerve alterations in early stage Fuchs’ endothelial corneal dystrophy: an in vivo confocal microscopy study

L M Schrems-Hoesl
W A Schrems
P Hamrah
Research16 Nov 2012
Eye

Volume: 27, P: 42-49
Influence of CT parameters upon the quantification of sarcopenia and myosteatosis: a study with human bodies

Issi R. Vedder
Stef Levolger
Alain R. Viddeleer
ResearchOpen Access08 Jan 2026
Scientific Reports

Volume: 16, P: 1-8
Q455V mutation in COL8A2 is associated with Fuchs' corneal dystrophy in Korean patients

J-W Mok
H-S Kim
C-K Joo
Research09 May 2008
Eye

Volume: 23, P: 895-903
Floral tributes

Early science texts carried illustrations that are master-works in their own right.

H. W. Lack
Research10 May 2001
Nature

Volume: 411, P: 137
Pre-operative hyphaema in Fuchs' heterochromic uveitis

Tamsin J Sleep
I H Chisholm
Correspondence01 Sept 1999
Eye

Volume: 13, P: 673-674
Actinide activities in water entering the northern North Sea

C. N. Murray
H. Kautsky
M. Domian
Research16 Nov 1978
Nature

Volume: 276, P: 225-230
Recent Antarctic Research

D. H. MALING
Research13 Oct 1956
Nature

Volume: 178, P: 773-775
Assessment of a three-generation pedigree with Fuchs endothelial corneal dystrophy with anticipation for expansion of the triplet repeat in the TCF4 gene

M A Greiner
D C Terveen
J H Fingert
Correspondence07 Apr 2017
Eye

Volume: 31, P: 1250-1252
Catalytic enantioselective synthesis of alkylidenecyclopropanes

A bifunctional iminophosphorane-catalysed, stereo-controlled deconjugation for the synthesis of highly enantioenriched alkylidenecyclopropanes is described, alongside computational studies elucidating the mechanistic pathway and origins of diastereoselectivity and enantioselectivity.

Jonathan C. Golec
Dong-Hang Tan
Darren J. Dixon
ResearchOpen Access11 Aug 2025
Nature

Volume: 645, P: 932-938
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

Elaine Fuchs and colleagues present mice conditionally lacking Tcf3 and Tcf4 in the skin and show that they play a role in long-term maintenance and wound repair of both epidermis and hair follicles.

Hoang Nguyen
Bradley J Merrill
Elaine Fuchs
Research30 Aug 2009
Nature Genetics

Volume: 41, P: 1068-1075
Inhibition of IRAK4 by microbial trimethylamine blunts metabolic inflammation and ameliorates glycemic control

The microbial metabolite trimethylamine (TMA), the precursor of TMAO, which is associated with adverse cardiometabolic outcomes, is shown to have beneficial metabolic and anti-inflammatory effects in the host in the context of obesity.

Julien Chilloux
Francois Brial
Marc-Emmanuel Dumas
ResearchOpen Access08 Dec 2025
Nature Metabolism

Volume: 7, P: 2531-2547
A missense mutation in type VII collagen in two affected siblings with recessive dystrophic epidermolysis bullosa

Angela M. Christiano
Daniel S. Greenspan
Jouni Uitto
Research01 May 1993
Nature Genetics

Volume: 4, P: 62-66
Defective Gene Product in dnaF Mutant of Escherichia coli

JAMES A. FUCHS
H. OLLE KARLSTRÖM
PETER REICHARD
Research19 Jul 1972
Nature New Biology

Volume: 238, P: 69-71
The oldest sepioid cephalopod from the Cretaceous discovered by Digital fossil-mining with zero-shot learning AI

The oldest sepioid in the Cretaceous shows intermediate morphologies between cuttlefish and bobtail squids, revealing their early evolution. This discovery was facilitated by Digital fossil-mining method incorporating a zero-shot learning AI model.

Kanta Sugiura
Shin Ikegami
Yasuhiro Iba
ResearchOpen Access16 Jan 2026
Communications Biology

P: 1-9
Observation of deuteron and antideuteron formation from resonance-decay nucleons

The ALICE Collaboration provides details on the microscopic mechanism that ends up creating antideuteron in high-energy proton–proton collisions at the Large Hadron Collider.

S. Acharya
A. Agarwal
N. Zurlo
ResearchOpen Access10 Dec 2025
Nature

Volume: 648, P: 306-311
Donor splice site mutation in keratin 5 causes in-frame removal of 22 amino acids of H1 and 1A rod domains in Dowling-Meara epidermolysis bullosa simplex

Elizabeth L Rugg
Marie-Odette Rachet-Préhu
Alain Hovnanian
Research05 May 1999
European Journal of Human Genetics

Volume: 7, P: 293-300
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

Urinary albumin-to-creatinine ratio (UCAR) is associated with various clinical outcomes such as kidney disease and cardiovascular disease. Here, the authors report genome-wide meta-analysis in over 500,000 individuals and find 68 UACR loci, followed by statistical fine-mapping, gene prioritization and experimental validation in flies.

Alexander Teumer
Yong Li
Anna Köttgen
ResearchOpen Access11 Sept 2019
Nature Communications

Volume: 10, P: 1-19
Asymmetric cell divisions promote Notch-dependent epidermal differentiation

This study focuses on developing mouse skin where mitotic basal progenitor cells switch from symmetric divisions to asymmetric division concomitant with stratification. Using a novel technical approach, the genetic pathway regulating spindle orientation is dissected, providing the first direct evidence that the proteins governing spindle orientation (LGN, NuMA and Dctn1) promote asymmetric cell divisions regulated by Notch signalling in mammalian cells in vivo.

Scott E. Williams
Slobodan Beronja
Elaine Fuchs
Research16 Feb 2011
Nature

Volume: 470, P: 353-358
Exercise facilitates post-stroke recovery through mitigation of neuronal hyperexcitability via interleukin-10 signaling

Exercise promotes recovery after stroke, but the underlying mechanisms are unclear. Here, the authors show that regulatory T cells enable exercise-induced repair by reducing neuronal hyperexcitability via interleukin-10, linking immunity to functional regeneration.

A. Schmidt-Pogoda
T. Ruck
J. Minnerup
ResearchOpen Access08 Oct 2025
Nature Communications

Volume: 16, P: 1-16
Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation

A conditional knockout of the transcription factor SRF in the mouse skin shows that SRF-mediated modulation of actin regulator transcription during development is essential for normal cortical network formation and correct spindle orientation in mitosis.

Chen Luxenburg
H. Amalia Pasolli
Elaine Fuchs
Research20 Feb 2011
Nature Cell Biology

Volume: 13, P: 203-214
Absolute Configuration of the Prostaglandins

D. H. NUGTEREN
D. A. VAN DORP
B. SAMUELSSON
Research01 Oct 1966
Nature

Volume: 212, P: 38-39
Keratin 16 and keratin 17 mutations cause pachyonychia congenita

W.H.I. McLean
E.L. Rugg
C.S. Munro
Research01 Mar 1995
Nature Genetics

Volume: 9, P: 273-278
Evolution of the African Cichlid Fishes: the Haplochromis Species-Flock in Lake Victoria

P. H. GREENWOOD
Research06 Jan 1951
Nature

Volume: 167, P: 19-20
MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters

Here the authors show that epigenetic regulation through the histone acetyltransferase MOF and the acetylation of histone H4 lysine 16 affect essential functions in the mitochondria and primary cilia. This regulation is important to promote epidermal differentiation and hair follicle formation.

Dongmei Wang
Haimin Li
Rui Yi
ResearchOpen Access21 Jul 2023
Nature Communications

Volume: 14, P: 1-17
On the Matter Thrown up During the Submarine Eruption North-West of Pantelleria, October 1891

GERARD W. BUTLER
GEO. H. PERRY
Research14 Jan 1892
Nature

Volume: 45, P: 251-252
Influence of a Magnetic Field on the Conductivity of Thin Metallic Films

E. H. SONDHEIMER
Research26 Nov 1949
Nature

Volume: 164, P: 920-921
Results of the Occultation of Regulus by Venus, July 7, 1959

G. de VAUCOULEURS
D. H. MENZEL
Research01 Oct 1960
Nature

Volume: 188, P: 28-33
Site of Phenylalanine Ammonia–Lyase Activity and Synthesis of Lignin during Xylem Differentiation

P. H. RUBERY
D. H. NORTHCOTE
Research21 Sept 1968
Nature

Volume: 219, P: 1230-1234
Temperature Independent Retention in Gas Chromatography

P. F. MCCREA
J. H. PURNELL
Research01 Jul 1968
Nature

Volume: 219, P: 261-262
Stabilization of Water Mists

H. S. EISNER
F. R. BROOKES
B. W. QUINCE
Research20 Dec 1958
Nature

Volume: 182, P: 1724
Missing links: Weber–Cockayne keratin mutations implicate the L12 linker domain in effective cytoskeleton function

E.L. Rugg
S.M. Morley
E.B. Lane
Research01 Nov 1993
Nature Genetics

Volume: 5, P: 294-300
Radio Observations of OH in the Interstellar Medium

S. WEINREB
A. H. BARRETT
J. C. HENRY
Research30 Nov 1963
Nature

Volume: 200, P: 829-831
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Identification of the genetic locus for keratosis palmaris et plantaris on chromosome 17 near the RARA and keratin type I genes

Evgeny I. Rogaev
Ekaterina A. Rogaeva
Peter H. St George-Hyslop
Research01 Oct 1993
Nature Genetics

Volume: 5, P: 158-162
Generation of region– and species–specific expressed gene probes from somatic cell hybrids

Keith W. Jones
Mario Chevrette
R. E. K. Fournier
Research01 Jul 1992
Nature Genetics

Volume: 1, P: 278-283
A mutation in the conserved helix termination peptide of keratin 5 in hereditary skin blistering

E. B. Lane
E. L. Rugg
R. A. J. Eady
Research19 Mar 1992
Nature

Volume: 356, P: 244-246
A KINETIC THEORY OF LIQUIDS

MAX BORN F.R.S.
H. S. GREEN
Research22 Feb 1947
Nature

Volume: 159, P: 251-254
Light Emission from Shock-front Compressed Air Layers in Tubes

C. H. JOHANSSON
T. SJÖLIN
Research26 Oct 1963
Nature

Volume: 200, P: 352-353
Free Amino-Acids on Human Fingers: The Question of Contamination in Microanalysis

J. ORÓ
H. B. SKEWES
Research01 Sept 1965
Nature

Volume: 207, P: 1042-1045
Structure and Function of E. Coli Ergosomes

T. STAEHELIN
C. C. BRINTON jun.
H. NOLL
Research31 Aug 1963
Nature

Volume: 199, P: 865-870
Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation

Xin et al. show, through intravital imaging, that Kras^G12D induces epithelial tissue deformation in a spatiotemporally specific manner by converting the pulsatile ERK signal fluctuation in stem cells into sustained activation.

Tianchi Xin
Sara Gallini
Valentina Greco
Research30 Apr 2024
Nature Cell Biology

Volume: 26, P: 859-867
The Electronic Charge

T. H. LABY
V. D. HOPPER
Research15 Jun 1940
Nature

Volume: 145, P: 932-933
Translation from unconventional 5′ start sites drives tumour initiation

The translation of upstream open reading frames in skin tumour models protects some cancer-related mRNAs from global reductions in protein synthesis during the early stages of tumour initiation, suggesting that unconventional translation has a crucial role in tumorigenesis.

Ataman Sendoel
Joshua G. Dunn
Elaine Fuchs
Research11 Jan 2017
Nature

Volume: 541, P: 494-499
Palladium-catalysed cross-coupling of lithium acetylides

The Sonogashira cross-coupling is a key strategy in modern synthesis for C–C bond formation and introduction of the versatile alkyne functionality into organic molecules. Now, a complementary method is reported based on the palladium-catalysed cross-coupling of lithium acetylides with aryl bromides.

Hugo Helbert
Paco Visser
Ben L. Feringa
Research13 Jul 2020
Nature Catalysis

Volume: 3, P: 664-671
Structure and Evolution of the Kenya Rift Valley

B. H. BAKER
J. WOHLENBERG
Research19 Feb 1971
Nature

Volume: 229, P: 538-542
Detection of carcinogen–DNA adducts by radioimmunoassay

MIRIAM C. POIRIER
STUART H. YUSPA
STEVEN BLOBSTEIN
Research10 Nov 1977
Nature

Volume: 270, P: 186-188

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