Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–5 of 5 results
Advanced filters: Author: H. Jelger Risselada Clear advanced filters

  • Here, the authors report water as a superior platform to suspend graphene compared to solid substrates that induce non-uniformity and do not provide structural flexibility. They utilize confocal Raman spectroscopy to study graphene floating freely on the surface of water to show that a liquid support relieves the pre-existing strain.

    • Liubov A. Belyaeva
    • Lin Jiang
    • Grégory F. Schneider
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • Synaptotagmin-1 is known to accelerate membrane fusion during neuronal exocytosis in response to Ca2+, but how it does this is unclear. By probing the activity of synaptotagmin-1 under conditions of low ionic strength, it is now shown that SNARE-mediated fusion is dependent on synaptotagmin-1, which tethers liposomes together but at distances too far for fusion. Ca2+ then induces synaptotagmin-1 to bring the liposomes closer together, allowing fusion to proceed.

    • Geert van den Bogaart
    • Shashi Thutupalli
    • Reinhard Jahn
    Research
    Nature Structural & Molecular Biology
    Volume: 18, P: 805-812

  • Interactions between synaptotagmin-1 and the SNARE syntaxin-1 are known to mediate synaptic-vesicle exocytosis. Fusion experiments with artificial lipid membranes combined with the crystal structure of synaptotagmin's C2B domain bound to phosphoserine indicate that PIP2 clusters, organized by syntaxin, act as molecular beacons for vesicle docking and direct Ca2+-dependent membrane fusion.

    • Alf Honigmann
    • Geert van den Bogaart
    • Reinhard Jahn
    Research
    Nature Structural & Molecular Biology
    Volume: 20, P: 679-686