Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

View all journals
Search
Log in

nature
search

Search

Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

British Journal of Cancer (37)
Leukemia (3)
Bone Marrow Transplantation (2)
Cell Death & Disease (2)
npj Parkinson's Disease (1)

Choose more journals

Article type Check one or more article types to show results from those article types only.

Research (45)
Reviews (1)

Subject Check one or more subjects to show results from those subjects only.

Biological techniques
Cancer
Cell biology
Diseases
Neurology
Neuroscience
Physiology

Date Choose a date option to show results from those dates only.

Today
Last 7 days
Last 30 days
Last 12 months
Last 2 years
Last 5 years

Custom date range

Clear all filters

Sort by:

Relevance

Date published (new to old)

Date published (old to new)

Showing 1–46 of 46 results

Advanced filters: Author: HM Pinedo Clear advanced filters

Theoretical and practical considerations for the measurement of P-glycoprotein function in acute myeloid leukemia

HJ Broxterman
J Lankelma
GJ Schuurhuis
Research01 Jul 1997
Leukemia

Volume: 11, P: 1110-1118
Prognostic role of clinical, pathological and biological characteristics in patients with locally advanced breast cancer

AH Honkoop
PJ van Diest
HM Pinedo
Research01 Feb 1998
British Journal of Cancer

Volume: 77, P: 621-626
Highly sensitive and specific detection of P-glycoprotein function for haematological and solid tumour cells using a novel nucleic acid stain

HJ Broxterman
GJ Schuurhuis
HM Pinedo
Research01 Oct 1997
British Journal of Cancer

Volume: 76, P: 1029-1034
Functional detection of MDR1/P170 and MRP/P190-mediated multidrug resistance in tumour cells by flow cytometry

N Feller
CM Kuiper
HJ Broxterman
Research01 Sept 1995
British Journal of Cancer

Volume: 72, P: 543-549
Determinants of CPT-11 and SN-38 activities in human lung cancer cells

J van Ark-Otte
MA Kedde
G Giaccone
Research01 Jun 1998
British Journal of Cancer

Volume: 77, P: 2171-2176
Characterization of human soft-tissue sarcoma xenografts for use in secondary drug screening

E Boven
HM Pinedo
G Giaccone
Research01 Dec 1998
British Journal of Cancer

Volume: 78, P: 1586-1593
Potent interaction of flavopiridol with MRP1

J H Hooijberg
H J Broxterman
HM Pinedo
ResearchOpen Access27 Aug 1999
British Journal of Cancer

Volume: 81, P: 269-276
The efficacy of the anthracycline prodrug daunorubicin-GA3 in human ovarian cancer xenografts

PHJ Houba
E Boven
HJ Haisma
Research01 Dec 1998
British Journal of Cancer

Volume: 78, P: 1600-1606
Do P-glycoprotein and major vault protein (MVP/LRP) expression correlate with in vitro daunorubicin resistance in acute myeloid leukemia?

HJ Broxterman
P Sonneveld
GJ Schuurhuis
Research05 Feb 1999
Leukemia

Volume: 13, P: 258-265
DT-diaphorase activity in normal and neoplastic human tissues; an indicator for sensitivity to bioreductive agents?

E Smitskamp-Wilms
G Giaccone
GJ Peters
Research01 Oct 1995
British Journal of Cancer

Volume: 72, P: 917-921
p53 and P-glycoprotein are often co-expressed and are associated with poor prognosis in breast cancer

SC Linn
AH Honkoop
G Giaccone
Research01 Jul 1996
British Journal of Cancer

Volume: 74, P: 63-68
CPT-11 sensitivity in relation to the expression of P170-glycoprotein and multidrug resistance-associated protein

WJM Jansen
TM Hulscher
E Boven
Research01 Feb 1998
British Journal of Cancer

Volume: 77, P: 359-365
Continuous infusion or subcutaneous injection of granulocyte-macrophage colony-stimulating factor: increased efficacy and reduced toxicity when given subcutaneously

AH Honkoop
K Hoekman
HM Pinedo
Research01 Oct 1996
British Journal of Cancer

Volume: 74, P: 1132-1136
Cortisol is transported by the multidrug resistance gene product P-glycoprotein

CK van Kalken
HJ Broxterman
G Giaccone
Research01 Feb 1993
British Journal of Cancer

Volume: 67, P: 284-289
Changes in subcellular doxorubicin distribution and cellular accumulation alone can largely account for doxorubicin resistance in SW-1573 lung cancer and MCF-7 breast cancer multidrug resistant tumour cells

GJ Schuurhuis
THM van Heijningen
J Lankelma
Research01 Nov 1993
British Journal of Cancer

Volume: 68, P: 898-908
Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells

CHM Versantvoort
GJ Schuurhuis
HJ Broxterman
Research01 Nov 1993
British Journal of Cancer

Volume: 68, P: 939-946
Enhanced therapeutic efficacy of 5'deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes

GJ Peters
BJM Braakhuis
HM Pinedo
Research01 Mar 1989
British Journal of Cancer

Volume: 59, P: 327-334
Early multidrug resistance, defined by changes in intracellular doxorubicin distribution, independent of P-glycoprotein

GJ Schuurhuis
HJ Broxterman
J Lankelma
Research01 Nov 1991
British Journal of Cancer

Volume: 64, P: 857-861
Cyclosporin A and verapamil have different effects on energy metabolism in multidrug-resistant tumour cells

HJ Broxterman
HM Pinedo
J Lankelma
Research01 Jul 1990
British Journal of Cancer

Volume: 62, P: 85-88
The influence of the schedule and the dose of gemcitabine on the anti-tumour efficacy in experimental human cancer

E Boven
H Schipper
HM Pinedo
Research01 Jul 1993
British Journal of Cancer

Volume: 68, P: 52-56
The polyoxyethylene castor oil Cremophor EL modifies multidrug resistance

GJ Schuurhuis
HJ Broxterman
J Lankelma
Research01 Oct 1990
British Journal of Cancer

Volume: 62, P: 591-594
The anti-tumour effects of the prodrugs N-l-leucyl-doxorubicin and vinblastine-isoleucinate in human ovarian cancer xenografts

E Boven
HR Hendriks
HM Pinedo
Research01 Dec 1992
British Journal of Cancer

Volume: 66, P: 1044-1047
Activity of GR30921X (NSC 382057) and GR63178A (NSC D611615) in human ovarian cancer lines

E Boven
CAM Erkelens
HM Pinedo
Research01 May 1990
British Journal of Cancer

Volume: 61, P: 709-711
In vitro biochemical and in vivo biological studies of the uridine 'rescue' of 5-fluorouracil

GJ Peters
J van Dijk
HM Pinedo
Research01 Mar 1988
British Journal of Cancer

Volume: 57, P: 259-265
A monoclonal antibody-β-glucuronidase conjugate as activator of the prodrug epirubicin-glucuronide for specific treatment of cancer

HJ Haisma
E Boven
HM Pinedo
Research01 Sept 1992
British Journal of Cancer

Volume: 66, P: 474-478
In vitro and in vivo studies on the combination of Brequinar sodium (DUP-785; NSC 368390) with 5-fluorouracil; effects of uridine

GJ Peters
I Kraal
HM Pinedo
Research01 Feb 1992
British Journal of Cancer

Volume: 65, P: 229-233
Comparison of the pharmacokinetics, biodistribution and dosimetry of monoclonal antibodies OC125, OV-TL 3, and 139H2 as IgG and F(ab')₂ fragments in experimental ovarian cancer

CFM Molthoff
HM Pinedo
E Boven
Research01 May 1992
British Journal of Cancer

Volume: 65, P: 677-683
Comparison of the monoclonal antibodies 17-1A and 323/A3: the influence of the affinity on tumour uptake and efficacy of radioimmunotherapy in human ovarian cancer xenografts

E Kievit
HM Pinedo
E Boven
Research01 Feb 1996
British Journal of Cancer

Volume: 73, P: 457-464
Importance of P450 reductase activity in determining sensitivity of breast tumour cells to the bioreductive drug, tirapazamine (SR 4233)

AV Patterson
HM Barham
IJ Stratford
Research01 Nov 1995
British Journal of Cancer

Volume: 72, P: 1144-1150
Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded ΦX174 DNA

DRA Mans
J Retèl
J Lankelma
Research01 Jul 1990
British Journal of Cancer

Volume: 62, P: 54-60
Calbindin and Girk2/Aldh1a1 define resilient vs vulnerable dopaminergic neurons in a primate Parkinson’s disease model

Natalia López-González del Rey
Nagore Hernández-Pinedo
Javier Blesa
ResearchOpen Access02 Sept 2024
npj Parkinson's Disease

Volume: 10, P: 1-15
Examination by laser scanning confocal fluorescence imaging microscopy of the subcellular localisation of anthracyclines in parent and multidrug resistant cell lines

HM Coley
WB Amos
P Workman
Research01 Jun 1993
British Journal of Cancer

Volume: 67, P: 1316-1323
Lobular panniculitis after subcutaneous administration of interleukin-2 (IL-2), and its exacerbation during intravenous therapy with IL-2

JW Baars
JLLM Coenen
HM Pinedo
Research01 Oct 1992
British Journal of Cancer

Volume: 66, P: 698-699
A pilot study to evaluate the effects of C1 esterase inhibitor on the toxicity of high-dose interleukin 2

AC Ogilvie
JW Baars
J Wagstaff
Research01 Mar 1994
British Journal of Cancer

Volume: 69, P: 596-598
Sequential cisplatin/cyclophosphamide chemotherapy and abdominopelvic radiotherapy in the management of advanced ovarian cancer

JA Green
HM Warenius
AJ Slater
Research01 Nov 1988
British Journal of Cancer

Volume: 58, P: 635-639
Response of peritoneal solid tumours after intraperitoneal chemohyperthermia treatment with cisplatin or carboplatin

G Los
MJH van Vugt
HM Pinedo
Research01 Feb 1994
British Journal of Cancer

Volume: 69, P: 235-241
Effects of interleukin-3 on myelosuppression induced by chemotherapy for ovarian cancer and small cell undifferentiated tumours

MW Dercksen
K Hoekman
HM Pinedo
Research01 Nov 1993
British Journal of Cancer

Volume: 68, P: 996-1003
Growth, morphology and chemosensitivity studies on postconfluent cells cultured in 'V'-bottomed microtiter plates

PE Pizao
DM Lyaruu
HM Pinedo
Research01 Oct 1992
British Journal of Cancer

Volume: 66, P: 660-665
Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition

Angiogenesis inhibitors are now being used in the treatment of patients with cancer. However, these agents can lead to toxicities. This Perspective discusses these toxicities and the possible molecular mechanisms behind them.

Henk. M. W. Verheul
Herbert M. Pinedo
Reviews01 Jun 2007
Nature Reviews Cancer

Volume: 7, P: 475-485
Generation and validation of a novel multitarget small molecule in glioblastoma

Aizpea Artetxe-Zurutuza
Nerea Iturrioz-Rodriguez
Ander Matheu
ResearchOpen Access04 Apr 2025
Cell Death & Disease

Volume: 16, P: 1-14
The activation of polymorphonuclear neutrophils and the complement system during immunotherapy with recombinant Interleukin-2

JW Baars
CE Hack
HM Pinedo
Research01 Jan 1992
British Journal of Cancer

Volume: 65, P: 96-101
P-glycoprotein in primary acute myeloid leukemia and treatment outcome of idarubicin/cytosine arabinoside-based induction therapy

HJ Broxterman
P Sonneveld
GJ Schuurhuis
Research06 Jun 2000
Leukemia

Volume: 14, P: 1018-1024
Extensive early apoptosis in frozen–thawed CD34-positive stem cells decreases threshold doses for haematological recovery after autologous peripheral blood progenitor cell transplantation

F de Boer
AM Dräger
GJ Schuurhuis
Research22 Feb 2002
Bone Marrow Transplantation

Volume: 29, P: 249-255
Do glutathione and related enzymes play a role in drug resistance in small cell lung cancer cell lines?

BG Campling
K Baer
SP Cole
Research01 Aug 1993
British Journal of Cancer

Volume: 68, P: 327-335
Changes in L-selectin expression on CD34-positive cells upon cryopreservation of peripheral blood stem cell transplants

F De Boer
AM Dräger
GJ Schuurhuis
Research03 Dec 1998
Bone Marrow Transplantation

Volume: 22, P: 1103-1110
Single-cell time-lapse imaging of intracellular O₂ in response to metabolic inhibition and mitochondrial cytochrome-c release

Heiko Düssmann
Sergio Perez-Alvarez
Jochen HM Prehn
ResearchOpen Access01 Jun 2017
Cell Death & Disease

Volume: 8, P: e2853