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Showing 1–2 of 2 results
Advanced filters: Author: Hachung Chung Clear advanced filters

  • Studies on the essentiality of Ku in human cells reveal that Ku interacts with diverse double-stranded RNA molecules, including antisense Alu, and enables tolerance of Alu sequence expansion in primates.

    • Yimeng Zhu
    • Angelina Li
    • Shan Zha
    Research
    Nature
    Volume: 643, P: 562-571

  • Mammalian genomes generate long non-coding RNAs, which are degraded by the RNA surveillance machinery. This regulated degradation is vital for various processes, including for genome integrity, stem cell pluripotency and immune cell activation. Consequently, defects in RNA surveillance cause human diseases and developmental disorders.

    • Lekha Nair
    • Hachung Chung
    • Uttiya Basu
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 21, P: 123-136