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Showing 1–5 of 5 results
Advanced filters: Author: Hanah Margalit Clear advanced filters

  • The RNA-binding protein CsrA switches from upregulation to downregulation of virulence genes in bacteria through unclear mechanisms. Here, the authors show that the switch between promoting and repressing virulence gene expression involves formation of a membraneless compartment containing CsrA, mRNAs, small regulatory RNAs and degradosome components.

    • Lior Aroeti
    • Netanel Elbaz
    • Ilan Rosenshine
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • TRS is a new method for determining 3’ transcript termini in bacteria, using data generated by the RNAtag-seq protocol. This methodology opens the door to study the evolution of transcription termini and their condition-dependent dynamics.

    • Amir Bar
    • Liron Argaman
    • Hanah Margalit
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • Ndd1 activates the transcription of mitotic regulators. Here the authors show that the ubiquitin ligase complex APC/CCdh1ubiquitinates Ndd1 as well as Ndd1 target genes, creating a feedforward loop that generates an early class of substrates that accumulate at S phase and a late class that accumulate at G2.

    • Julia Sajman
    • Drora Zenvirth
    • Michael Brandeis
    Research
    Nature Communications
    Volume: 6, P: 1-10