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Advanced filters: Author: Hanh Hanuschka Clear advanced filters
  • The SpyTag/SpyCatcher protein ligation technology is valuable in many applications, but few methods exist for controlling reactivity. Here the authors report a method for controlling SpyCatcher activity via S-thiolation of engineered cysteines, demonstrating the value of their technology for the rapid generation of bispecific antibodies.

    • Christian Hentrich
    • Mateusz Putyrski
    • Francisco Ylera
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-15