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Advanced filters: Author: Hanie Samimi Clear advanced filters

Pathogenic tau-induced piRNA depletion promotes neuronal death through transposable element dysregulation in neurodegenerative tauopathies

Transposable elements, or ‘jumping genes’, constitute ~45% of the human genome. Sun et. al. report that jumping gene dysregulation is a pharmacologically targetable driver of cell death in neurodegenerative tauopathies, including Alzheimer’s disease.

Wenyan Sun
Hanie Samimi
Bess Frost
Research23 Jul 2018
Nature Neuroscience

Volume: 21, P: 1038-1048
Integrating DNA methylation and gene expression data in a single gene network using the iNETgrate package

Sogand Sajedi
Ghazal Ebrahimi
Habil Zare
ResearchOpen Access08 Dec 2023
Scientific Reports

Volume: 13, P: 1-10

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Pathogenic tau-induced piRNA depletion promotes neuronal death through transposable element dysregulation in neurodegenerative tauopathies

Integrating DNA methylation and gene expression data in a single gene network using the iNETgrate package

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