Hans Wehrl et al. use a multimodal approach to demonstrate the feasibility of measuring functional brain responses in activated and resting states with PET and MRI simultaneously. Using this method, which allows brain function studies to be conducted on multiple time and metabolic scales, they could tease apart the complex relationships between neural activity, blood flow and oxygenation that form the basis of the blood oxygen level–dependent (BOLD) effect.
- Hans F Wehrl
- Mosaddek Hossain
- Bernd J Pichler
