Nature Search

Genoketides A1 and A2, New Octaketides and Biosynthetic Intermediates of Chrysophanol Produced by Streptomyces sp. AK 671

Hans-Peter Fiedler
Anke Dieter
Gerhard Bringmann
Research01 Jul 2008
The Journal of Antibiotics

Volume: 61, P: 464-473
Cystoid edema, neovascularization and inflammatory processes in the murine Norrin-deficient retina

Susanne C. Beck
Marcus Karlstetter
Thomas Langmann
ResearchOpen Access13 Apr 2018
Scientific Reports

Volume: 8, P: 1-16
Hotspot motion caused the Hawaiian-Emperor Bend and LLSVPs are not fixed

Controversy surrounds the fixity of both hotspots and large low shear velocity provinces (LLSVPs). Here, the authors present new paleomagnetic data to show that the great bend in the Hawaiian-Emperor seamount chain can be attributed to mantle plume motion and that LLSVPs are mobile.

Richard K. Bono
John A. Tarduno
Hans-Peter Bunge
ResearchOpen Access29 Jul 2019
Nature Communications

Volume: 10, P: 1-9
Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy

A product of the soluble epoxide hydrolase enzyme, 19,20-dihydroxydocosapentaenoic acid (19,20-DHDP), is implicated in the pathogenesis of diabetic retinopathy; levels of 19,20-DHDP increase in the retinas of mice and humans with diabetes, and inhibition of its production can rescue vascular abnormalities in a mouse model of the disease.

Jiong Hu
Sarah Dziumbla
Ingrid Fleming
Research06 Dec 2017
Nature

Volume: 552, P: 248-252
Hypothalamic atrophy in primary lateral sclerosis, assessed by convolutional neural network-based automatic segmentation

Jan Kassubek
Francesco Roselli
Hans-Peter Müller
ResearchOpen Access10 Jan 2025
Scientific Reports

Volume: 15, P: 1-6
Nataxazole, a New Benzoxazole Derivative with Antitumor Activity Produced by Streptomyces sp. Tü 6176^†

Patricia S M Sommer
Rosemary C Almeida
Hans-Peter Fiedler
Research01 Nov 2008
The Journal of Antibiotics

Volume: 61, P: 683-686
A mouse model to identify cooperating signaling pathways in cancer

The mouse cancer model 'Multi-Hit' allows for the evaluation of oncogene cooperativities in tumor development based on stochastic Cre-recombination events. Cells with cooperating oncogenes are positively selected and give rise to tumors. The approach is used to study Ras downstream effector pathways in tumorigenesis.

Monica Musteanu
Leander Blaas
Robert Eferl
Research05 Aug 2012
Nature Methods

Volume: 9, P: 897-900
Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma

SUMOylation is a post-translational modification that has been shown to be altered in cancer. Here, the authors show that loss of the SUMO isopeptidase SENP6 leads to unrestricted SUMOylation and genomic instability promoting lymphomagenesis and generating vulnerability to PARP inhibition.

Markus Schick
Le Zhang
Ulrich Keller
ResearchOpen Access12 Jan 2022
Nature Communications

Volume: 13, P: 1-16
Bendigoles A~C, New Steroids from Gordonia australis Acta 2299

Kathrin Schneider
Ellen Graf
Hans-Peter Fiedler
Research01 Jun 2008
The Journal of Antibiotics

Volume: 61, P: 356-364
Elloxazinones A and B, New Aminophenoxazinones from Streptomyces griseus Acta 2871^†

Ellen Graf
Kathrin Schneider
Hans-Peter Fiedler
Research01 Apr 2007
The Journal of Antibiotics

Volume: 60, P: 277-284
Repositioning of the global epicentre of non-optimal cholesterol

From 1980 to 2018, the levels of total and non-high-density lipoprotein cholesterol increased in low- and middle-income countries, especially in east and southeast Asia, and decreased in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe.

Cristina Taddei
Bin Zhou
Majid Ezzati
ResearchOpen Access03 Jun 2020
Nature

Volume: 582, P: 73-77
Toward the blood-borne miRNome of human diseases

Expression profiles of several hundred microRNAs in the blood of individuals with disease, including autoimmune disease, cancers, cardiovascular disease and chronic inflammatory disease are reported.

Andreas Keller
Petra Leidinger
Eckart Meese
Research04 Sept 2011
Nature Methods

Volume: 8, P: 841-843
Enhancing post-kidney transplant prognostication: an interpretable machine learning approach for longitudinal outcome prediction

Bowen Fan
Manuel Schürch
Patrick Yerly
ResearchOpen Access18 Nov 2025
npj Digital Medicine

Volume: 8, P: 1-11
Widespread deoxygenation of temperate lakes

Analysis of temperate lakes finds a widespread decline in dissolved oxygen concentrations in surface and deep waters, which is associated with reduced solubility at warmer surface water temperatures and increased stratification at depth.

Stephen F. Jane
Gretchen J. A. Hansen
Kevin C. Rose
Research02 Jun 2021
Nature

Volume: 594, P: 66-70
Body fat compartment determination by encoder–decoder convolutional neural network: application to amyotrophic lateral sclerosis

Ina Vernikouskaya
Hans-Peter Müller
Volker Rasche
ResearchOpen Access01 Apr 2022
Scientific Reports

Volume: 12, P: 1-9
A Rydberg quantum simulator

Building on recent experimental advances in controlling individual Rydberg atoms, theoretical work proposes a ‘Rydberg quantum simulator’. Such a system would be suitable for efficiently simulating other quantum systems with many-body interactions and strongly correlated ground states.

Hendrik Weimer
Markus Müller
Hans Peter Büchler
Research14 Mar 2010
Nature Physics

Volume: 6, P: 382-388
Corticoefferent pathology distribution in amyotrophic lateral sclerosis: in vivo evidence from a meta-analysis of diffusion tensor imaging data

Martin Gorges
Kelly Del Tredici
Jan Kassubek
ResearchOpen Access18 Oct 2018
Scientific Reports

Volume: 8, P: 1-10
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

Jürgen Soutschek
Akin Akinc
Hans-Peter Vornlocher
Research11 Nov 2004
Nature

Volume: 432, P: 173-178
Organic coating on biochar explains its nutrient retention and stimulation of soil fertility

Biochar promotes plant growth via a slow release of nutrients; however, a mechanistic understanding of nutrient storage in biochar is lacking. Here, using high-resolution spectromicroscopy and mass spectrometry, the authors identify an organic coating on co-composted particles that enhances nutrient retention.

Nikolas Hagemann
Stephen Joseph
Andreas Kappler
ResearchOpen Access20 Oct 2017
Nature Communications

Volume: 8, P: 1-11
Retymicin, Galtamycin B, Saquayamycin Z and Ribofuranosyllumichrome, Novel Secondary Metabolites from Micromonospora sp. Tü 6368

Karsten Ströch
Axel Zeeck
Hans-Peter Fiedler
Research01 Feb 2005
The Journal of Antibiotics

Volume: 58, P: 103-110
Retymicin, Galtamycin B, Saquayamycin Z and Ribofuranosyllumichrome, Novel Secondary Metabolites from Micromonospora sp. Tü 6368

Noémi Antal
Hans-Peter Fiedler
Axel Zeeck
Research01 Feb 2005
The Journal of Antibiotics

Volume: 58, P: 95-102
AI-assisted quantification of hypothalamic atrophy in amyotrophic lateral sclerosis by convolutional neural network-based automatic segmentation

Ina Vernikouskaya
Hans-Peter Müller
Volker Rasche
ResearchOpen Access06 Dec 2023
Scientific Reports

Volume: 13, P: 1-11
Detection and phylogenetic analysis of blood-associated pathogens from spleen samples of wild raccoons (Procyon lotor) in Germany

Maria Sophia Unterköfler
Aria Schwingshandl
Mike Heddergott
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-8
Clinical and neuroimaging disparity between Chinese and German patients with cerebral small vessel disease: a comparative study

Junlong Shu
Hermann Neugebauer
Wei Zhang
ResearchOpen Access27 Dec 2019
Scientific Reports

Volume: 9, P: 1-7
Intact sensory-motor network structure and function in far from onset premanifest Huntington’s disease

Martin Gorges
Hans-Peter Müller
Michael Orth
ResearchOpen Access07 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
Specificity of eccentric hamstring training and the lack of consistency between strength assessments using conventional test devices

Hans-Peter Wiesinger
Manuel Scharinger
Erich Müller
ResearchOpen Access28 Jun 2021
Scientific Reports

Volume: 11, P: 1-13
Granulation compared to co-application of biochar plus mineral fertilizer and its impacts on crop growth and nutrient leaching

Jannis Grafmüller
Jens Möllmer
Nikolas Hagemann
ResearchOpen Access17 Jul 2024
Scientific Reports

Volume: 14, P: 1-15
Functional Polymorphisms in Dopaminergic Genes Modulate Neurobehavioral and Neurophysiological Consequences of Sleep Deprivation

Sebastian C. Holst
Thomas Müller
Hans-Peter Landolt
ResearchOpen Access10 Apr 2017
Scientific Reports

Volume: 7, P: 1-11
Functional connectivity changes resemble patterns of pTDP-43 pathology in amyotrophic lateral sclerosis

Ines Schulthess
Martin Gorges
Jan Kassubek
ResearchOpen Access08 Dec 2016
Scientific Reports

Volume: 6, P: 1-10
Plant growth improvement mediated by nitrate capture in co-composted biochar

Claudia I. Kammann
Hans-Peter Schmidt
Stephen Joseph
ResearchOpen Access09 Jun 2015
Scientific Reports

Volume: 5, P: 1-13
Effects of COMT genotype and tolcapone on lapses of sustained attention after sleep deprivation in healthy young men

Amandine Valomon
Sebastian C. Holst
Hans-Peter Landolt
Research05 Feb 2018
Neuropsychopharmacology

Volume: 43, P: 1599-1607
Erratum: Plant growth improvement mediated by nitrate capture in co-composted biochar

Claudia I. Kammann
Hans-Peter Schmidt
Stephen Joseph
Amendments and Corrections05 Aug 2015
Scientific Reports

Volume: 5, P: 1
Rapid adaptation drives invasion of airway donor microbiota by Pseudomonas after lung transplantation

M. Beaume
T. Köhler
Patrick Yerly
ResearchOpen Access17 Jan 2017
Scientific Reports

Volume: 7, P: 1-10
CRTC2 polymorphism as a risk factor for the incidence of metabolic syndrome in patients with solid organ transplantation

L Quteineh
P-Y Bochud
Patrick Yerly
Research08 Dec 2015
The Pharmacogenomics Journal

Volume: 17, P: 69-75

Search

Genoketides A1 and A2, New Octaketides and Biosynthetic Intermediates of Chrysophanol Produced by Streptomyces sp. AK 671

Cystoid edema, neovascularization and inflammatory processes in the murine Norrin-deficient retina

Hotspot motion caused the Hawaiian-Emperor Bend and LLSVPs are not fixed

Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy

Hypothalamic atrophy in primary lateral sclerosis, assessed by convolutional neural network-based automatic segmentation

Nataxazole, a New Benzoxazole Derivative with Antitumor Activity Produced by Streptomyces sp. Tü 6176^†

A mouse model to identify cooperating signaling pathways in cancer

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma

Bendigoles A~C, New Steroids from Gordonia australis Acta 2299

Elloxazinones A and B, New Aminophenoxazinones from Streptomyces griseus Acta 2871^†

Repositioning of the global epicentre of non-optimal cholesterol

Toward the blood-borne miRNome of human diseases

Enhancing post-kidney transplant prognostication: an interpretable machine learning approach for longitudinal outcome prediction

Widespread deoxygenation of temperate lakes

Body fat compartment determination by encoder–decoder convolutional neural network: application to amyotrophic lateral sclerosis

A Rydberg quantum simulator

Corticoefferent pathology distribution in amyotrophic lateral sclerosis: in vivo evidence from a meta-analysis of diffusion tensor imaging data

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

Organic coating on biochar explains its nutrient retention and stimulation of soil fertility

Retymicin, Galtamycin B, Saquayamycin Z and Ribofuranosyllumichrome, Novel Secondary Metabolites from Micromonospora sp. Tü 6368

Retymicin, Galtamycin B, Saquayamycin Z and Ribofuranosyllumichrome, Novel Secondary Metabolites from Micromonospora sp. Tü 6368

AI-assisted quantification of hypothalamic atrophy in amyotrophic lateral sclerosis by convolutional neural network-based automatic segmentation

Detection and phylogenetic analysis of blood-associated pathogens from spleen samples of wild raccoons (Procyon lotor) in Germany

Clinical and neuroimaging disparity between Chinese and German patients with cerebral small vessel disease: a comparative study

Intact sensory-motor network structure and function in far from onset premanifest Huntington’s disease

Specificity of eccentric hamstring training and the lack of consistency between strength assessments using conventional test devices

Granulation compared to co-application of biochar plus mineral fertilizer and its impacts on crop growth and nutrient leaching

Functional Polymorphisms in Dopaminergic Genes Modulate Neurobehavioral and Neurophysiological Consequences of Sleep Deprivation

Functional connectivity changes resemble patterns of pTDP-43 pathology in amyotrophic lateral sclerosis

Plant growth improvement mediated by nitrate capture in co-composted biochar

Effects of COMT genotype and tolcapone on lapses of sustained attention after sleep deprivation in healthy young men

Erratum: Plant growth improvement mediated by nitrate capture in co-composted biochar

Rapid adaptation drives invasion of airway donor microbiota by Pseudomonas after lung transplantation

CRTC2 polymorphism as a risk factor for the incidence of metabolic syndrome in patients with solid organ transplantation

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