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Showing 1–4 of 4 results

Advanced filters: Author: Haobin Ren Clear advanced filters

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation

Diffuse intrinsic pontine gliomas exhibit a characteristic mutation of lysine 27 to methionine (K27M) in genes encoding histone H3.3. Here the authors show that the H3.3K27M mutation imposes a specific pattern of H3.3K27 methylation by altering the target search dynamics of PcG proteins.

Roubina Tatavosian
Huy Nguyen Duc
Xiaojun Ren
ResearchOpen Access25 May 2018
Nature Communications

Volume: 9, P: 1-16
Fear extinction is regulated by the activity of long noncoding RNAs at the synapse

Synaptic activity controls the extinction of conditioned fear. Here the authors discovered a new way that the brain controls memories of fear: a long noncoding RNA called Gas5 that coordinates the activity of RNA granules in the synaptic compartment.

Wei-Siang Liau
Qiongyi Zhao
Timothy W. Bredy
ResearchOpen Access22 Nov 2023
Nature Communications

Volume: 14, P: 1-16
Lactate-activated GPR81/FARP1 signaling drives insulin-independent glucose uptake and metabolic control

Yaxin Niu
Shengmin Hu
Linzhang Huang
Research13 Jan 2026
Cell Research

Volume: 36, P: 137-151
Investigation of transverse crack spacing in an asphalt pavement with a semi-rigid base

Jiangcai Chen
Hengzhen Li
Xiaofeng Huang
ResearchOpen Access27 Oct 2022
Scientific Reports

Volume: 12, P: 1-17