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Showing 1–4 of 4 results
Advanced filters: Author: Harith Akram Clear advanced filters

  • Li et al. analyzed structural connectivity of deep brain stimulation electrodes in 50 patients suffering from obsessive-compulsive disorder operated at four centers. Connectivity to a specific tract within the anterior limb of the internal capsule was associated with optimal treatment response across cohorts, surgeons and centers.

    • Ningfei Li
    • Juan Carlos Baldermann
    • Andreas Horn
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Hollunder et al. identify networks where deep brain stimulation reduces symptoms for Parkinson’s disease, Tourette’s syndrome, dystonia and obsessive-compulsive disorder. This revealed a fronto-rostral topography that segregates the frontal cortex.

    • Barbara Hollunder
    • Jill L. Ostrem
    • Andreas Horn
    ResearchOpen Access
    Nature Neuroscience
    Volume: 27, P: 573-586

  • In Parkinson’s disease (PD), beta frequency oscillations are synchronised across the cortico-basal-ganglia circuit. The authors show in human participants that high beta frequencies propagate from the cortex to the basal ganglia via the hyperdirect pathway, indicating a pathophysiological role for this pathway in PD.

    • Ashwini Oswal
    • Chunyan Cao
    • Vladimir Litvak
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14

  • Deep brain stimulation (DBS) is a well-established approach for treating movement disorders such as Parkinson disease, dystonia and essential tremor. However, the outcomes are variable, and researchers are now exploring artificial intelligence-based strategies to help improve DBS procedures.

    • Patricia Limousin
    • Harith Akram
    Comments & Opinion
    Nature Reviews Neurology
    Volume: 19, P: 451-452