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Showing 1–21 of 21 results

Advanced filters: Author: Harold L Moses Clear advanced filters

Murine Leukaemia C-type Virus associated with Functional Murine Carcinomas of Endocrine Origin

WILLIAM M. MITCHELL
HAROLD L. MOSES
JOSEF KORINEK
Research26 May 1971
Nature New Biology

Volume: 231, P: 99-100
Production and auto-induction of transforming growth factor-α in human keratinocytes

Robert J. Coffey Jr
Rik Derynck
Mark R. Pittelkow
Research27 Aug 1987
Nature

Volume: 328, P: 817-820
Infectious Mononucleosis: Continuous Suspension Culture of Peripheral Blood Leucocytes

PHILIP R. GLADE
JULIUS A. KASEL
LAWRENCE N. CHESSIN
Research10 Feb 1968
Nature

Volume: 217, P: 564-565
Tumor suppressor genes in the TGF–β signaling pathway?

Loss of response to TGF-βs may be an important step in the development and progression of cancer. Recent studies show that receptors and proteins involved in TGF-β signaling may act as tumor suppressors.

Rosa Serra
Harold L. Moses
News & Views01 Apr 1996
Nature Medicine

Volume: 2, P: 390-391
Choroplast Pigments of Deuterated Green Algae

HAROLD H. STRAIN
HENRY L. CRESPI
JOSEPH J. KATZ
Research29 Aug 1959
Nature

Volume: 184, P: 730-731
Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

Donald Ingber
Takeshi Fujita
Judah Folkman
Research06 Dec 1990
Nature

Volume: 348, P: 555-557
Dwarfs and Dwarf Worship

HAROLD CRICHTON-BROWNE
Research21 Jan 1892
Nature

Volume: 45, P: 269-271
The roles of TGFβ in the tumour microenvironment

The influence of the microenvironment on tumour progression is becoming clearer. This Review addresses the role of transforming growth factor-β in the regulation of components of the tumour microenvironment.

Michael Pickup
Sergey Novitskiy
Harold L. Moses
Reviews17 Oct 2013
Nature Reviews Cancer

Volume: 13, P: 788-799
TGF-β helps cells fly solo

Intravital imaging demonstrates that TGF-β signalling regulates the mode of cancer cell motility. Cells with active TGF-β signalling migrate as single cells and are capable of hematogenous and lymphatic spread, whereas cells lacking TGF-β signalling invade lymphatics collectively.

Lauren A. Matise
Michael W. Pickup
Harold L. Moses
News & Views18 Oct 2009
Nature Cell Biology

Volume: 11, P: 1281-1284
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

Impaired TGF-β signaling due to SMAD4 mutation in PDAC tumors initiates a STAT3-dependent signaling cascade that leads to increased stromal stiffening and disease progression.

Hanane Laklai
Yekaterina A Miroshnikova
Valerie M Weaver
Research18 Apr 2016
Nature Medicine

Volume: 22, P: 497-505
Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

Hanane Laklai
Yekaterina A. Miroshnikova
Valerie M. Weaver
Amendments and Corrections28 Nov 2023
Nature Medicine

Volume: 30, P: 908
TGFβ: the molecular Jekyll and Hyde of cancer

Transforming growth factor-β (TGFβ) can function either within the tumour cell or through host–tumour cell interactions. The complex nature of TGFβ signalling and crosstalk in the tumour microenvironment presents unique challenges and opportunities to develop therapeutic intervention strategies.

Brian Bierie
Harold L. Moses
Reviews01 Jul 2006
Nature Reviews Cancer

Volume: 6, P: 506-520
Inactivation of TGF-β signaling in hepatocytes results in an increased proliferative response after partial hepatectomy

Judith Romero-Gallo
Elif G Sozmen
William M Grady
Research07 Feb 2005
Oncogene

Volume: 24, P: 3028-3041
A global reference for human genetic variation

Results for the final phase of the 1000 Genomes Project are presented including whole-genome sequencing, targeted exome sequencing, and genotyping on high-density SNP arrays for 2,504 individuals across 26 populations, providing a global reference data set to support biomedical genetics.

Adam Auton
Gonçalo R. Abecasis
Gonçalo R. Abecasis
ResearchOpen Access30 Sept 2015
Nature

Volume: 526, P: 68-74
Stromal fibroblasts in cancer initiation and progression

Neil A. Bhowmick
Eric G. Neilson
Harold L. Moses
Reviews17 Nov 2004
Nature

Volume: 432, P: 332-337
kallisto, bustools and kb-python for quantifying bulk, single-cell and single-nucleus RNA-seq

Kallisto, bustools and kb-python are a set of tools for quantifying bulk, single-cell and single-nucleus RNA-seq. Together, this set of free, open-source software tools can produce gene expression quantification from raw sequencing reads.

Delaney K. Sullivan
Kyung Hoi (Joseph) Min
Lior Pachter
Protocols10 Oct 2024
Nature Protocols

Volume: 20, P: 587-607
TGF-β1 Regulates the Expression of Multiple Max-Interacting Transcription Factors in Balb/MK Cells: Implications for Understanding the Mechanism of Action of TGF-β1

Daniel J Satterwhite
Raymond L White
Harold L Moses
Research01 Jul 2001
Pediatric Research

Volume: 50, P: 67-75
Blocking CXCLs–CXCR2 axis in tumor–stromal interactions contributes to survival in a mouse model of pancreatic ductal adenocarcinoma through reduced cell invasion/migration and a shift of immune-inflammatory microenvironment

Makoto Sano
Hideaki Ijichi
Kazuhiko Koike
ResearchOpen Access18 Jan 2019
Oncogenesis

Volume: 8, P: 1-12
Soluble VCAM-1 promotes gemcitabine resistance via macrophage infiltration and predicts therapeutic response in pancreatic cancer

Ryota Takahashi
Hideaki Ijichi
Kazuhiko Koike
ResearchOpen Access03 Dec 2020
Scientific Reports

Volume: 10, P: 1-13
Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer

Yi Li
Wendy P Hively
Harold E Varmus
Research07 Mar 2000
Oncogene

Volume: 19, P: 1002-1009
Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP- and HGF-mediated signaling networks

Nikki Cheng
Neil A Bhowmick
Harold L Moses
Research18 Apr 2005
Oncogene

Volume: 24, P: 5053-5068