Nature Search

Mirtron-mediated RNA knockdown/replacement therapy for the treatment of dominant retinitis pigmentosa

Rhodopsin-related dominant retinitis pigmentosa is a degenerative disease of the retina of the eye for which there is no current treatment. In this study, the authors use a novel form of RNA-interference- artificial mirtrons- to slow retinal degeneration in a mouse model of the disease.

Harry O. Orlans
Michelle E. McClements
Robert E. MacLaren
ResearchOpen Access16 Aug 2021
Nature Communications

Volume: 12, P: 1-13
Using QR smartphone technology to improve patient communication and information distribution

Afshaun Azad
D. Alistair H. Laidlaw
Harry O. Orlans
Research30 Aug 2021
Eye

Volume: 36, P: 1321-1322
Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia

The long-term follow-up results of a phase 1/2 retinal gene therapy clinical trial for choroideremia (NCT01461213) support the safety and efficacy of the treatment.

Kanmin Xue
Jasleen K Jolly
Robert E. MacLaren
Research08 Oct 2018
Nature Medicine

Volume: 24, P: 1507-1512
Direct ophthalmoscopy should be taught within the context of its limitations

H O Orlans
Correspondence27 Nov 2015
Eye

Volume: 30, P: 326-327
In vitro antibiotic susceptibility patterns of bacterial keratitis isolates in Oxford, UK: a 10-year review

H O Orlans
S J Hornby
I C J W Bowler
Research21 Jan 2011
Eye

Volume: 25, P: 489-493
Comment on: ‘Sector retinitis pigmentosa caused by mutations of the RHO gene’

Harry O. Orlans
Robert E. MacLaren
Correspondence28 Oct 2019
Eye

Volume: 34, P: 1477-1478

Quick links

Search

Filter By:

Mirtron-mediated RNA knockdown/replacement therapy for the treatment of dominant retinitis pigmentosa

Using QR smartphone technology to improve patient communication and information distribution

Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia

Direct ophthalmoscopy should be taught within the context of its limitations

In vitro antibiotic susceptibility patterns of bacterial keratitis isolates in Oxford, UK: a 10-year review

Comment on: ‘Sector retinitis pigmentosa caused by mutations of the RHO gene’

Search

Quick links