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Showing 1–8 of 8 results
Advanced filters: Author: Hashem El-Serag Clear advanced filters

  • Chronic HCV infection is a global health problem. In this Review, the authors describe the global burden of hepatitis C and HCV-related disease, including hepatocellular carcinoma, cirrhosis and extrahepatic manifestations. How the new direct-acting antiviral agents might influence disease burden is also discussed.

    • Aaron P. Thrift
    • Hashem B. El-Serag
    • Fasiha Kanwal
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 14, P: 122-132

  • The prevalence of nonalcoholic fatty liver disease (NAFLD)-related hepatocellular carcinoma (HCC) is projected to continue to increase worldwide. In this Review, Huang, El-Serag and Loomba discuss the global epidemiology and risk factors for NAFLD-related HCC, and propose strategies to tackle this problem.

    • Daniel Q. Huang
    • Hashem B. El-Serag
    • Rohit Loomba
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 18, P: 223-238

  • Chemoprevention for patients with Barrett’s oesophagus remains a controversial topic. Results of the first randomized trial of chemoprevention using a proton pump inhibitor with or without aspirin were recently reported. We highlight strengths and weaknesses in the design of the trial and discuss the clinical implications of the findings.

    • Nisreen S. Husain
    • Hashem B. El-Serag
    News & Views
    Nature Reviews Clinical Oncology
    Volume: 15, P: 728-730

  • Globally, gastric cancer is a common and highly fatal cancer with two anatomical subtypes, non-cardia and cardia gastric cancer. Helicobacter pylori causes almost 90% of distal gastric cancers worldwide. The authors of this Review summarize the current epidemiology of gastric cancer and the evidence and implications of primary and secondary prevention efforts.

    • Aaron P. Thrift
    • Theresa Nguyen Wenker
    • Hashem B. El-Serag
    Reviews
    Nature Reviews Clinical Oncology
    Volume: 20, P: 338-349

  • In this Review, Llovet and colleagues discuss advances in our knowledge of the pathogenesis and clinical management of nonalcoholic steatohepatitis-related hepatocellular carcinoma. They also discuss future prospects and unmet needs.

    • Josep M. Llovet
    • Catherine E. Willoughby
    • Scott L. Friedman
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 20, P: 487-503

  • Metabolic (dysfunction)-associated fatty liver disease (MAFLD) is a chronic liver disease typically associated with obesity. This Review discusses the epidemiology and physiology of individuals of normal weight with MAFLD and provides insights into their metabolic health and metabolic adaptation.

    • Mohammed Eslam
    • Hashem B. El-Serag
    • Jacob George
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 19, P: 638-651

  • Gastro-oesophageal reflux disease is common in adults and children. This Primer covers current knowledge of the different aspects of the disease in these populations, including its epidemiology, pathophysiology, diagnosis, treatment and prognosis as well as the quality of life of patients.

    • Ronnie Fass
    • Guy E. Boeckxstaens
    • Michael F. Vaezi
    Reviews
    Nature Reviews Disease Primers
    Volume: 7, P: 1-23