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Nature Genetics (1)

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Advanced filters: Author: Havva Ortabozkoyun Clear advanced filters

CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters

Genome-wide screens identify several genes, including MAZ, required for CTCF-mediated insulation. MAZ interacts with cohesin, and MAZ motif deletions derepress posterior Hox gene expression, leading to homeotic transformations in mouse.

Havva Ortabozkoyun
Pin-Yao Huang
Danny Reinberg
ResearchOpen Access10 Feb 2022
Nature Genetics

Volume: 54, P: 202-212

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CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters

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