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Advanced filters: Author: Hayley M. Todesco Clear advanced filters

  • The role of non-cancer cells infected by oncolytic viruses (OV) in cancer regression remains elusive. Here the authors engineer OV-sensitive and OV-resistant cancer cell lines and show that OV infection of non-cancer cells can elicit effective antitumour immunity via enhancing DC function and CD8+ T cell activation.

    • Jahanara Rajwani
    • Daniil Vishnevskiy
    • Douglas J. Mahoney
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-20